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P2X7 in Cancer: From Molecular Mechanisms to Therapeutics
P2X7 is a transmembrane receptor expressed in multiple cell types including neurons, dendritic cells, macrophages, monocytes, B and T cells where it can drive a wide range of physiological responses from pain transduction to immune response. Upon activation by its main ligand, extracellular ATP, P2X...
Autores principales: | Lara, Romain, Adinolfi, Elena, Harwood, Catherine A., Philpott, Mike, Barden, Julian A., Di Virgilio, Francesco, McNulty, Shaun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287489/ https://www.ncbi.nlm.nih.gov/pubmed/32581786 http://dx.doi.org/10.3389/fphar.2020.00793 |
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