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A Teleophthalmology Support System Based on the Visibility of Retinal Elements Using the CNNs

This paper proposes a teleophthalmology support system in which we use algorithms of object detection and semantic segmentation, such as faster region-based CNN (FR-CNN) and SegNet, based on several CNN architectures such as: Vgg16, MobileNet, AlexNet, etc. These are used to segment and analyze the...

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Autores principales: Calderon-Auza, Gustavo, Carrillo-Gomez, Cesar, Nakano, Mariko, Toscano-Medina, Karina, Perez-Meana, Hector, Gonzalez-H. Leon, Ana, Quiroz-Mercado, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287628/
https://www.ncbi.nlm.nih.gov/pubmed/32429400
http://dx.doi.org/10.3390/s20102838
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author Calderon-Auza, Gustavo
Carrillo-Gomez, Cesar
Nakano, Mariko
Toscano-Medina, Karina
Perez-Meana, Hector
Gonzalez-H. Leon, Ana
Quiroz-Mercado, Hugo
author_facet Calderon-Auza, Gustavo
Carrillo-Gomez, Cesar
Nakano, Mariko
Toscano-Medina, Karina
Perez-Meana, Hector
Gonzalez-H. Leon, Ana
Quiroz-Mercado, Hugo
author_sort Calderon-Auza, Gustavo
collection PubMed
description This paper proposes a teleophthalmology support system in which we use algorithms of object detection and semantic segmentation, such as faster region-based CNN (FR-CNN) and SegNet, based on several CNN architectures such as: Vgg16, MobileNet, AlexNet, etc. These are used to segment and analyze the principal anatomical elements, such as optic disc (OD), region of interest (ROI) composed by the macular region, real retinal region, and vessels. Unlike the conventional retinal image quality assessment system, the proposed system provides some possible reasons about the low-quality image to support the operator of an ophthalmoscope and patient to acquire and transmit a better-quality image to central eye hospital for its diagnosis. The proposed system consists of four steps: OD detection, OD quality analysis, obstruction detection of the region of interest (ROI), and vessel segmentation. For the OD detection, artefacts and vessel segmentation, the FR-CNN and SegNet are used, while for the OD quality analysis, we use transfer learning. The proposed system provides accuracies of 0.93 for the OD detection, 0.86 for OD image quality, 1.0 for artefact detection, and 0.98 for vessel segmentation. As the global performance metric, the kappa-based agreement score between ophthalmologist and the proposed system is calculated, which is higher than the score between ophthalmologist and general practitioner.
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spelling pubmed-72876282020-06-15 A Teleophthalmology Support System Based on the Visibility of Retinal Elements Using the CNNs Calderon-Auza, Gustavo Carrillo-Gomez, Cesar Nakano, Mariko Toscano-Medina, Karina Perez-Meana, Hector Gonzalez-H. Leon, Ana Quiroz-Mercado, Hugo Sensors (Basel) Article This paper proposes a teleophthalmology support system in which we use algorithms of object detection and semantic segmentation, such as faster region-based CNN (FR-CNN) and SegNet, based on several CNN architectures such as: Vgg16, MobileNet, AlexNet, etc. These are used to segment and analyze the principal anatomical elements, such as optic disc (OD), region of interest (ROI) composed by the macular region, real retinal region, and vessels. Unlike the conventional retinal image quality assessment system, the proposed system provides some possible reasons about the low-quality image to support the operator of an ophthalmoscope and patient to acquire and transmit a better-quality image to central eye hospital for its diagnosis. The proposed system consists of four steps: OD detection, OD quality analysis, obstruction detection of the region of interest (ROI), and vessel segmentation. For the OD detection, artefacts and vessel segmentation, the FR-CNN and SegNet are used, while for the OD quality analysis, we use transfer learning. The proposed system provides accuracies of 0.93 for the OD detection, 0.86 for OD image quality, 1.0 for artefact detection, and 0.98 for vessel segmentation. As the global performance metric, the kappa-based agreement score between ophthalmologist and the proposed system is calculated, which is higher than the score between ophthalmologist and general practitioner. MDPI 2020-05-16 /pmc/articles/PMC7287628/ /pubmed/32429400 http://dx.doi.org/10.3390/s20102838 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Calderon-Auza, Gustavo
Carrillo-Gomez, Cesar
Nakano, Mariko
Toscano-Medina, Karina
Perez-Meana, Hector
Gonzalez-H. Leon, Ana
Quiroz-Mercado, Hugo
A Teleophthalmology Support System Based on the Visibility of Retinal Elements Using the CNNs
title A Teleophthalmology Support System Based on the Visibility of Retinal Elements Using the CNNs
title_full A Teleophthalmology Support System Based on the Visibility of Retinal Elements Using the CNNs
title_fullStr A Teleophthalmology Support System Based on the Visibility of Retinal Elements Using the CNNs
title_full_unstemmed A Teleophthalmology Support System Based on the Visibility of Retinal Elements Using the CNNs
title_short A Teleophthalmology Support System Based on the Visibility of Retinal Elements Using the CNNs
title_sort teleophthalmology support system based on the visibility of retinal elements using the cnns
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287628/
https://www.ncbi.nlm.nih.gov/pubmed/32429400
http://dx.doi.org/10.3390/s20102838
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