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Lower Plasma Melatonin Levels Predict Worse Long-Term Survival in Pulmonary Arterial Hypertension
Exogenous melatonin has been reported to be beneficial in the treatment of pulmonary hypertension (PH) in animal models. Multiple mechanisms are involved, with melatonin exerting anti-oxidant and anti-inflammatory effects, as well as inducing vasodilation and cardio-protection. However, endogenous l...
Autores principales: | Cai, Zongye, Klein, Theo, Geenen, Laurie W., Tu, Ly, Tian, Siyu, van den Bosch, Annemien E., de Rijke, Yolanda B., Reiss, Irwin K. M., Boersma, Eric, Duncker, Dirk J., Boomars, Karin A., Guignabert, Christophe, Merkus, Daphne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287676/ https://www.ncbi.nlm.nih.gov/pubmed/32344923 http://dx.doi.org/10.3390/jcm9051248 |
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