Cargando…

An Ecologically Valid, Longitudinal, and Unbiased Assessment of Treatment Efficacy in Alzheimer Disease (the EVALUATE-AD Trial): Proof-of-Concept Study

BACKGROUND: The current clinical trial assessment methodology relies on a combination of self-report measures, cognitive and physical function tests, and biomarkers. This methodology is limited by recall bias and recency effects in self-reporting and by assessments that are brief, episodic, and clin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thomas, Neil William Douglas, Beattie, Zachary, Marcoe, Jennifer, Wright, Kirsten, Sharma, Nicole, Mattek, Nora, Dodge, Hiroko, Wild, Katherine, Kaye, Jeffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JMIR Publications 2020
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287724/ https://www.ncbi.nlm.nih.gov/pubmed/32459184 http://dx.doi.org/10.2196/17603

Ejemplares similares

Older Adults’ Experience of Health and Life Events as Reported Online Over 150 Consecutive Weeks
por: Kaye, Jeffrey, et al.
Publicado: (2020)

Sensing a problem: Proof of concept for characterizing and predicting agitation
por: Au‐Yeung, Wan‐Tai M., et al.
Publicado: (2020)

USE OF TECHNOLOGY BY FOUR DIVERSE COHORTS OF OLDER ADULTS: FINDINGS FROM THE CART STUDY
por: Wild, Katherine, et al.
Publicado: (2019)

Association Between Mild Cognitive Impairment and Seasonal Rest-Activity Patterns of Older Adults
por: Reynolds, Christina, et al.
Publicado: (2022)

Reproducibility and replicability of high‐frequency, in‐home digital biomarkers in reducing sample sizes for clinical trials
por: Wu, Chao‐Yi, et al.
Publicado: (2021)

Changes in Physical Activity during COVID-19 Pandemic in Urban and Rural Older Veterans and their Cohabitants
por: Wu, Chao-Yi, et al.
Publicado: (2020)

Increased Blue Mood and Loneliness during COVID-19 Pandemic in a Veteran Cohort
por: Mattek, Nora, et al.
Publicado: (2020)

Aging and Financial Capacity: Cognitive Correlates of an Early Indicator of Functional Decline
por: Wild, Katherine, et al.
Publicado: (2020)

Preferences of NIA Alzheimer's Disease Research Center participants regarding remote assessment during the COVID‐19 pandemic
por: Nunnerley, Michael, et al.
Publicado: (2022)

Correlating continuously captured home-based digital biomarkers of daily function with postmortem neurodegenerative neuropathology
por: Hantke, Nathan C., et al.
Publicado: (2023)

Online monitoring of financial capacity in older adults: Feasibility and initial findings
por: Wild, Katherine, et al.
Publicado: (2022)

Using Continuous Passive Assessment Technology to Describe Health and Behavior Patterns Preceding and Following a Cancer Diagnosis in Older Adults: Proof-of-Concept Case Series Study
por: Wu, Chao-Yi, et al.
Publicado: (2023)

Activity and Cognition in Older Adults With and Without Sleep Apnea
por: Mattek, Nora, et al.
Publicado: (2020)

Pervasive Computing Technologies to Continuously Assess Alzheimer’s Disease Progression and Intervention Efficacy
por: Lyons, Bayard E., et al.
Publicado: (2015)

Corrigendum: Pervasive computing technologies to continuously assess Alzheimer's disease progression and intervention efficacy
por: Lyons, Bayard E., et al.
Publicado: (2015)

DAYS AND NIGHTS OF DYADS: EXAMINING BEHAVIORAL INTERDEPENDENCE IN CO-RESIDING COUPLES USING ACTIGRAPHY
por: Miller, Lyndsey M, et al.
Publicado: (2019)

Computer mouse movement patterns: A potential marker of mild cognitive impairment
por: Seelye, Adriana, et al.
Publicado: (2015)

Current State of Digital Biomarker Technologies for Real-Life, Home-Based Monitoring of Cognitive Function for Mild Cognitive Impairment to Mild Alzheimer Disease and Implications for Clinical Care: Systematic Review
por: Piau, Antoine, et al.
Publicado: (2019)

Characteristics associated with willingness to participate in a randomized controlled behavioral clinical trial using home-based personal computers and a webcam
por: Dodge, Hiroko H, et al.
Publicado: (2014)

Successful Transitions to Remote Assessments and Technology Installations due to COVID-19: The I-CONECT Project
por: Nguyen, Khoa, et al.
Publicado: (2020)

Older Adults’ Daily Activity and Mood Changes Detected During the COVID-19 Pandemic Using Remote Unobtrusive Monitoring Technologies
por: Leese, Mira I, et al.
Publicado: (2021)

Web-enabled conversational interactions as a method to improve cognitive functions: Results of a 6-week randomized controlled trial
por: Dodge, Hiroko H., et al.
Publicado: (2015)

In-Home Mobility Frequency and Stability in Older Adults Living Alone With or Without MCI: Introduction of New Metrics
por: Wu, Chao-Yi, et al.
Publicado: (2021)

Use of High-Frequency In-Home Monitoring Data May Reduce Sample Sizes Needed in Clinical Trials
por: Dodge, Hiroko H., et al.
Publicado: (2015)

Memory complaints in older adults: Prognostic value and stability in reporting over time
por: Howieson, Diane B, et al.
Publicado: (2015)

Social Markers of Mild Cognitive Impairment: Proportion of Word Counts in Free Conversational Speech
por: Dodge, Hiroko H., et al.
Publicado: (2015)

I-CONECT: CHALLENGES AND OPPORTUNITIES
por: Dodge, Hiroko H, et al.
Publicado: (2019)

Investigating the concept of participant burden in aging technology research
por: Kabacińska, Katarzyna, et al.
Publicado: (2020)

Executive function predicts risk of falls in older adults without balance impairment
por: Buracchio, Teresa J, et al.
Publicado: (2011)

Less Daily Computer Use is Related to Smaller Hippocampal Volumes in Cognitively Intact Elderly
por: Silbert, Lisa C., et al.
Publicado: (2016)

Feasibility of Unbiased RNA Profiling of Colorectal Tumors: A Proof of Principle
por: Moshayoff, Vardit, et al.
Publicado: (2016)

Application of In-Home Monitoring Data to Transition Decisions in Continuing Care Retirement Communities: Usability Study
por: Wild, Katherine, et al.
Publicado: (2021)

An Investigation of Levetiracetam in Alzheimer’s Disease (ILiAD): a double-blind, placebo-controlled, randomised crossover proof of concept study
por: Sen, Arjune, et al.
Publicado: (2021)

Time Out-of-Home and Cognitive, Physical, and Emotional Wellbeing of Older Adults: A Longitudinal Mixed Effects Model
por: Petersen, Johanna, et al.
Publicado: (2015)

Plasma lipoproteome in Alzheimer’s disease: a proof-of-concept study
por: Li, Danni, et al.
Publicado: (2018)

Stability and Variability of Indoor Room Transitions and Mild Cognitive Impairment in Older Adults
por: Wu, Chao-Yi, et al.
Publicado: (2021)

Comparing the Emotion Status of Individuals With MCI to Their Cognitively Normal Counterparts: I-CONECT Project
por: Yu, Kexin, et al.
Publicado: (2021)

COLLABORATIVE AGING RESEARCH USING TECHNOLOGY: NEW PATHWAYS FORWARD
por: Kaye, Jeffrey, et al.
Publicado: (2019)

Randomized, controlled, proof-of-concept trial of MK-7622 in Alzheimer's disease
por: Voss, Tiffini, et al.
Publicado: (2018)

Plasma omega-3 PUFA and white matter mediated executive decline in older adults
por: Bowman, Gene L., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_halabeo1esneaohucp2dpb7343