Cargando…
Mathematical Model Predicts Effective Strategies to Inhibit VEGF-eNOS Signaling
The endothelial nitric oxide synthase (eNOS) signaling pathway in endothelial cells has multiple physiological significances. It produces nitric oxide (NO), an important vasodilator, and enables a long-term proliferative response, contributing to angiogenesis. This signaling pathway is mediated by v...
Autores principales: | Wu, Qianhui, Finley, Stacey D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287924/ https://www.ncbi.nlm.nih.gov/pubmed/32357492 http://dx.doi.org/10.3390/jcm9051255 |
Ejemplares similares
-
Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes
por: Advani, Andrew, et al.
Publicado: (2013) -
Computer Simulation of TSP1 Inhibition of VEGF–Akt–eNOS: An Angiogenesis Triple Threat
por: Bazzazi, Hojjat, et al.
Publicado: (2018) -
Heterozygous eNOS Deficient Mice as a Model to Examine the Effects of eNOS Haploinsufficiency on the Cerebral Circulation
por: Didion, Sean P.
Publicado: (2017) -
Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009) -
Predictive model identifies strategies to enhance TSP1-mediated apoptosis signaling
por: Wu, Qianhui, et al.
Publicado: (2017)