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Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study

Background: Recent articles have hypothesized a possible correlation between dental implants dissolution products and peri-implantitis. The null hypothesis tested in this case-control study was that there would be no differences in salivary concentrations of titanium (Ti), vanadium (V), nickel (Ni)...

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Autores principales: Papi, Piero, Raco, Andrea, Pranno, Nicola, Di Murro, Bianca, Passarelli, Pier Carmine, D’Addona, Antonio, Pompa, Giorgio, Barbieri, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288178/
https://www.ncbi.nlm.nih.gov/pubmed/32349296
http://dx.doi.org/10.3390/jcm9051264
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author Papi, Piero
Raco, Andrea
Pranno, Nicola
Di Murro, Bianca
Passarelli, Pier Carmine
D’Addona, Antonio
Pompa, Giorgio
Barbieri, Maurizio
author_facet Papi, Piero
Raco, Andrea
Pranno, Nicola
Di Murro, Bianca
Passarelli, Pier Carmine
D’Addona, Antonio
Pompa, Giorgio
Barbieri, Maurizio
author_sort Papi, Piero
collection PubMed
description Background: Recent articles have hypothesized a possible correlation between dental implants dissolution products and peri-implantitis. The null hypothesis tested in this case-control study was that there would be no differences in salivary concentrations of titanium (Ti), vanadium (V), nickel (Ni) and arsenic (As) ions among patients with dental implants, healthy (Group A) or affected by peri-implantitis (Group B), compared to subjects without implants and/or metallic prosthetic restorations (Group C). Methods: Inductively coupled plasma mass spectrometry was used to analyze saliva samples. One-way repeated-measure analysis of variance (ANOVA) was used to identify statistically significant differences in the salivary level of Ti, V, Ni and As between the three groups. Results: A total of 100 patients were enrolled in the study (42 males and 58 females), distributed in three groups: 50 patients in Group C, 26 patients in Group B and 24 patients Group B. In our study, concentrations of metallic ions were higher in Group A and B, compared to the control group, with the exception of vanadium. However, there were no statistically significant differences (p > 0.05) for metallic ions concentrations between Group A and Group B. Conclusions: Based on our results, there are no differences in titanium or other metals concentrations in saliva of patients with healthy or diseased implants.
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spelling pubmed-72881782020-06-17 Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study Papi, Piero Raco, Andrea Pranno, Nicola Di Murro, Bianca Passarelli, Pier Carmine D’Addona, Antonio Pompa, Giorgio Barbieri, Maurizio J Clin Med Article Background: Recent articles have hypothesized a possible correlation between dental implants dissolution products and peri-implantitis. The null hypothesis tested in this case-control study was that there would be no differences in salivary concentrations of titanium (Ti), vanadium (V), nickel (Ni) and arsenic (As) ions among patients with dental implants, healthy (Group A) or affected by peri-implantitis (Group B), compared to subjects without implants and/or metallic prosthetic restorations (Group C). Methods: Inductively coupled plasma mass spectrometry was used to analyze saliva samples. One-way repeated-measure analysis of variance (ANOVA) was used to identify statistically significant differences in the salivary level of Ti, V, Ni and As between the three groups. Results: A total of 100 patients were enrolled in the study (42 males and 58 females), distributed in three groups: 50 patients in Group C, 26 patients in Group B and 24 patients Group B. In our study, concentrations of metallic ions were higher in Group A and B, compared to the control group, with the exception of vanadium. However, there were no statistically significant differences (p > 0.05) for metallic ions concentrations between Group A and Group B. Conclusions: Based on our results, there are no differences in titanium or other metals concentrations in saliva of patients with healthy or diseased implants. MDPI 2020-04-27 /pmc/articles/PMC7288178/ /pubmed/32349296 http://dx.doi.org/10.3390/jcm9051264 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Papi, Piero
Raco, Andrea
Pranno, Nicola
Di Murro, Bianca
Passarelli, Pier Carmine
D’Addona, Antonio
Pompa, Giorgio
Barbieri, Maurizio
Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study
title Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study
title_full Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study
title_fullStr Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study
title_full_unstemmed Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study
title_short Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study
title_sort salivary levels of titanium, nickel, vanadium, and arsenic in patients treated with dental implants: a case-control study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288178/
https://www.ncbi.nlm.nih.gov/pubmed/32349296
http://dx.doi.org/10.3390/jcm9051264
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