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Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5

Farnesoid X receptor (FXR) and Takeda G-protein coupled receptor 5 (TGR5) are the two known bile acid (BA) sensitive receptors and are expressed in the intestine and liver as well as in extra-enterohepatic tissues. The physiological effects of extra-enterohepatic FXR/TRG5 remain unclear. Further, th...

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Detalles Bibliográficos
Autores principales:	Trammell, Samuel A. J., Svenningsen, Jens S., Holst, Jens J., Gillum, Matthew P., Kuhre, Rune E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288213/ https://www.ncbi.nlm.nih.gov/pubmed/32443832 http://dx.doi.org/10.3390/molecules25102371

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