Association Analysis and Meta-Analysis of Multi-Allelic Variants for Large-Scale Sequence Data

There is great interest in understanding the impact of rare variants in human diseases using large sequence datasets. In deep sequence datasets of >10,000 samples, ~10% of the variant sites are observed to be multi-allelic. Many of the multi-allelic variants have been shown to be functional and d...

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Detalles Bibliográficos
Autores principales: Jiang, Yu, Chen, Sai, Wang, Xingyan, Liu, Mengzhen, Iacono, William G., Hewitt, John K., Hokanson, John E., Krauter, Kenneth, Laakso, Markku, Li, Kevin W., Lutz, Sharon M., McGue, Matthew, Pandit, Anita, Zajac, Gregory J.M., Boehnke, Michael, Abecasis, Goncalo R., Vrieze, Scott I., Jiang, Bibo, Zhan, Xiaowei, Liu, Dajiang J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288273/
https://www.ncbi.nlm.nih.gov/pubmed/32466134
http://dx.doi.org/10.3390/genes11050586

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