Cargando…

Role of Reconstructive Microsurgery in Tubal Infertility in Young Women

Aim: Here, we retrospectively analyzed the success rate of reconstructive microsurgery for tubal infertility (RMTI) as a “first-line” approach to achieving tubal reversal and pregnancy after tubal infertility. Patients and Methods: During 9 consecutive years (2005–2014), 96 patients diagnosed with o...

Descripción completa

Detalles Bibliográficos
Autores principales: Barac, Sorin, Jiga, Lucian Petru, Rata, Andreea, Sas, Ioan, Onofrei, Roxana Ramona, Ionac, Mihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288274/
https://www.ncbi.nlm.nih.gov/pubmed/32370016
http://dx.doi.org/10.3390/jcm9051300
_version_ 1783545241079382016
author Barac, Sorin
Jiga, Lucian Petru
Rata, Andreea
Sas, Ioan
Onofrei, Roxana Ramona
Ionac, Mihai
author_facet Barac, Sorin
Jiga, Lucian Petru
Rata, Andreea
Sas, Ioan
Onofrei, Roxana Ramona
Ionac, Mihai
author_sort Barac, Sorin
collection PubMed
description Aim: Here, we retrospectively analyzed the success rate of reconstructive microsurgery for tubal infertility (RMTI) as a “first-line” approach to achieving tubal reversal and pregnancy after tubal infertility. Patients and Methods: During 9 consecutive years (2005–2014), 96 patients diagnosed with obstructive tubal infertility underwent RMTI (tubal reversal, salpingostomy, and/or tubal implantation) in our centre. The outcomes are presented in terms of tubal reversal rate and pregnancy and correlated with age, level of tubal obstruction, and duration of tubal infertility. Results: The overall tubal reversal rate was 87.56% (84 patients). The 48-month cumulative pregnancy rate was 78.04% (64 patients), of which seven ectopic pregnancies occurred (8.53%). The reversibility rate for women under 35 yo was 90.47%, with a birth rate of 73.01%. The reconstruction at the infundibular segments favored higher ectopic pregnancy rates (four ectopic pregnancies for anastomosis at infundibular level—57.14%, two for ampullary level—28.57%, and one for replantation technique—14.28%), with a significant value for p < 0.05. Conclusions: In the context of IVF “industrialization”, reconstructive microsurgery for tubal infertility has become increasingly less favored. However, under available expertise and proper indication, RMTI can be successfully used to restore a woman’s ability to conceive naturally with a high postoperative pregnancy rate overall, especially in women under 35 yo.
format Online
Article
Text
id pubmed-7288274
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-72882742020-06-17 Role of Reconstructive Microsurgery in Tubal Infertility in Young Women Barac, Sorin Jiga, Lucian Petru Rata, Andreea Sas, Ioan Onofrei, Roxana Ramona Ionac, Mihai J Clin Med Article Aim: Here, we retrospectively analyzed the success rate of reconstructive microsurgery for tubal infertility (RMTI) as a “first-line” approach to achieving tubal reversal and pregnancy after tubal infertility. Patients and Methods: During 9 consecutive years (2005–2014), 96 patients diagnosed with obstructive tubal infertility underwent RMTI (tubal reversal, salpingostomy, and/or tubal implantation) in our centre. The outcomes are presented in terms of tubal reversal rate and pregnancy and correlated with age, level of tubal obstruction, and duration of tubal infertility. Results: The overall tubal reversal rate was 87.56% (84 patients). The 48-month cumulative pregnancy rate was 78.04% (64 patients), of which seven ectopic pregnancies occurred (8.53%). The reversibility rate for women under 35 yo was 90.47%, with a birth rate of 73.01%. The reconstruction at the infundibular segments favored higher ectopic pregnancy rates (four ectopic pregnancies for anastomosis at infundibular level—57.14%, two for ampullary level—28.57%, and one for replantation technique—14.28%), with a significant value for p < 0.05. Conclusions: In the context of IVF “industrialization”, reconstructive microsurgery for tubal infertility has become increasingly less favored. However, under available expertise and proper indication, RMTI can be successfully used to restore a woman’s ability to conceive naturally with a high postoperative pregnancy rate overall, especially in women under 35 yo. MDPI 2020-05-01 /pmc/articles/PMC7288274/ /pubmed/32370016 http://dx.doi.org/10.3390/jcm9051300 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Barac, Sorin
Jiga, Lucian Petru
Rata, Andreea
Sas, Ioan
Onofrei, Roxana Ramona
Ionac, Mihai
Role of Reconstructive Microsurgery in Tubal Infertility in Young Women
title Role of Reconstructive Microsurgery in Tubal Infertility in Young Women
title_full Role of Reconstructive Microsurgery in Tubal Infertility in Young Women
title_fullStr Role of Reconstructive Microsurgery in Tubal Infertility in Young Women
title_full_unstemmed Role of Reconstructive Microsurgery in Tubal Infertility in Young Women
title_short Role of Reconstructive Microsurgery in Tubal Infertility in Young Women
title_sort role of reconstructive microsurgery in tubal infertility in young women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288274/
https://www.ncbi.nlm.nih.gov/pubmed/32370016
http://dx.doi.org/10.3390/jcm9051300
work_keys_str_mv AT baracsorin roleofreconstructivemicrosurgeryintubalinfertilityinyoungwomen
AT jigalucianpetru roleofreconstructivemicrosurgeryintubalinfertilityinyoungwomen
AT rataandreea roleofreconstructivemicrosurgeryintubalinfertilityinyoungwomen
AT sasioan roleofreconstructivemicrosurgeryintubalinfertilityinyoungwomen
AT onofreiroxanaramona roleofreconstructivemicrosurgeryintubalinfertilityinyoungwomen
AT ionacmihai roleofreconstructivemicrosurgeryintubalinfertilityinyoungwomen