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Role of Reconstructive Microsurgery in Tubal Infertility in Young Women
Aim: Here, we retrospectively analyzed the success rate of reconstructive microsurgery for tubal infertility (RMTI) as a “first-line” approach to achieving tubal reversal and pregnancy after tubal infertility. Patients and Methods: During 9 consecutive years (2005–2014), 96 patients diagnosed with o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288274/ https://www.ncbi.nlm.nih.gov/pubmed/32370016 http://dx.doi.org/10.3390/jcm9051300 |
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author | Barac, Sorin Jiga, Lucian Petru Rata, Andreea Sas, Ioan Onofrei, Roxana Ramona Ionac, Mihai |
author_facet | Barac, Sorin Jiga, Lucian Petru Rata, Andreea Sas, Ioan Onofrei, Roxana Ramona Ionac, Mihai |
author_sort | Barac, Sorin |
collection | PubMed |
description | Aim: Here, we retrospectively analyzed the success rate of reconstructive microsurgery for tubal infertility (RMTI) as a “first-line” approach to achieving tubal reversal and pregnancy after tubal infertility. Patients and Methods: During 9 consecutive years (2005–2014), 96 patients diagnosed with obstructive tubal infertility underwent RMTI (tubal reversal, salpingostomy, and/or tubal implantation) in our centre. The outcomes are presented in terms of tubal reversal rate and pregnancy and correlated with age, level of tubal obstruction, and duration of tubal infertility. Results: The overall tubal reversal rate was 87.56% (84 patients). The 48-month cumulative pregnancy rate was 78.04% (64 patients), of which seven ectopic pregnancies occurred (8.53%). The reversibility rate for women under 35 yo was 90.47%, with a birth rate of 73.01%. The reconstruction at the infundibular segments favored higher ectopic pregnancy rates (four ectopic pregnancies for anastomosis at infundibular level—57.14%, two for ampullary level—28.57%, and one for replantation technique—14.28%), with a significant value for p < 0.05. Conclusions: In the context of IVF “industrialization”, reconstructive microsurgery for tubal infertility has become increasingly less favored. However, under available expertise and proper indication, RMTI can be successfully used to restore a woman’s ability to conceive naturally with a high postoperative pregnancy rate overall, especially in women under 35 yo. |
format | Online Article Text |
id | pubmed-7288274 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72882742020-06-17 Role of Reconstructive Microsurgery in Tubal Infertility in Young Women Barac, Sorin Jiga, Lucian Petru Rata, Andreea Sas, Ioan Onofrei, Roxana Ramona Ionac, Mihai J Clin Med Article Aim: Here, we retrospectively analyzed the success rate of reconstructive microsurgery for tubal infertility (RMTI) as a “first-line” approach to achieving tubal reversal and pregnancy after tubal infertility. Patients and Methods: During 9 consecutive years (2005–2014), 96 patients diagnosed with obstructive tubal infertility underwent RMTI (tubal reversal, salpingostomy, and/or tubal implantation) in our centre. The outcomes are presented in terms of tubal reversal rate and pregnancy and correlated with age, level of tubal obstruction, and duration of tubal infertility. Results: The overall tubal reversal rate was 87.56% (84 patients). The 48-month cumulative pregnancy rate was 78.04% (64 patients), of which seven ectopic pregnancies occurred (8.53%). The reversibility rate for women under 35 yo was 90.47%, with a birth rate of 73.01%. The reconstruction at the infundibular segments favored higher ectopic pregnancy rates (four ectopic pregnancies for anastomosis at infundibular level—57.14%, two for ampullary level—28.57%, and one for replantation technique—14.28%), with a significant value for p < 0.05. Conclusions: In the context of IVF “industrialization”, reconstructive microsurgery for tubal infertility has become increasingly less favored. However, under available expertise and proper indication, RMTI can be successfully used to restore a woman’s ability to conceive naturally with a high postoperative pregnancy rate overall, especially in women under 35 yo. MDPI 2020-05-01 /pmc/articles/PMC7288274/ /pubmed/32370016 http://dx.doi.org/10.3390/jcm9051300 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Barac, Sorin Jiga, Lucian Petru Rata, Andreea Sas, Ioan Onofrei, Roxana Ramona Ionac, Mihai Role of Reconstructive Microsurgery in Tubal Infertility in Young Women |
title | Role of Reconstructive Microsurgery in Tubal Infertility in Young Women |
title_full | Role of Reconstructive Microsurgery in Tubal Infertility in Young Women |
title_fullStr | Role of Reconstructive Microsurgery in Tubal Infertility in Young Women |
title_full_unstemmed | Role of Reconstructive Microsurgery in Tubal Infertility in Young Women |
title_short | Role of Reconstructive Microsurgery in Tubal Infertility in Young Women |
title_sort | role of reconstructive microsurgery in tubal infertility in young women |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288274/ https://www.ncbi.nlm.nih.gov/pubmed/32370016 http://dx.doi.org/10.3390/jcm9051300 |
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