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Haplotypes of the Mutated SIRT2 Promoter Contributing to Transcription Factor Binding and Type 2 Diabetes Susceptibility

Genetic variability is an important causative factor for susceptibility and pathogenesis of type 2 diabetes (T2D). Histone deacetylase, sirtuin 2 (SIRT2), plays regulatory roles in glucose metabolism and insulin sensitivity. However, whether the SIRT2 variants or haplotypes contribute to T2D risk re...

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Detalles Bibliográficos
Autores principales:	Zheng, Xiao, Li, Jiajun, Sheng, Jie, Dai, Yang, Wang, Yue, Liu, Jinbiao, Xu, Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288287/ https://www.ncbi.nlm.nih.gov/pubmed/32438712 http://dx.doi.org/10.3390/genes11050569

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