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Association of Body Mass Index and Waist Circumference with All-Cause Mortality in Hemodialysis Patients

In this study based on a large nationally representative sample of Korean adults, we investigated the potential associations of the body mass index (BMI) and waist circumference (WC) with mortality in patients undergoing hemodialysis. We obtained the data of 18,699 participants >20 years of age w...

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Autores principales: Kim, Chang Seong, Han, Kyung-Do, Choi, Hong Sang, Bae, Eun Hui, Ma, Seong Kwon, Kim, Soo Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288310/
https://www.ncbi.nlm.nih.gov/pubmed/32365666
http://dx.doi.org/10.3390/jcm9051289
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author Kim, Chang Seong
Han, Kyung-Do
Choi, Hong Sang
Bae, Eun Hui
Ma, Seong Kwon
Kim, Soo Wan
author_facet Kim, Chang Seong
Han, Kyung-Do
Choi, Hong Sang
Bae, Eun Hui
Ma, Seong Kwon
Kim, Soo Wan
author_sort Kim, Chang Seong
collection PubMed
description In this study based on a large nationally representative sample of Korean adults, we investigated the potential associations of the body mass index (BMI) and waist circumference (WC) with mortality in patients undergoing hemodialysis. We obtained the data of 18,699 participants >20 years of age who were followed up with for 4 years and for whom BMI and WC information were available, using a nationally representative dataset from the Korean National Health Insurance System. Patients were stratified into five levels by their baseline BMI and into six levels by their WC (5-cm increments). A total of 4975 deaths occurred during a median follow-up period of 48.2 months. Participants with a higher BMI had a lower mortality rate than those with a lower BMI. In a fully adjusted Cox regression analysis, being overweight and obese was associated with a significantly lower relative risk of all-cause mortality relative to the reference group. Conversely, the mortality rate was higher among participants with a high WC than among those with a low WC. Participants with the highest WC had a higher risk of mortality, while those with the lowest WC level had a significantly lower risk of mortality. In conclusion, all-cause mortality was positively associated with WC, a measure of abdominal obesity, and inversely associated with BMI, a measure of body volume, in patients undergoing hemodialysis.
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spelling pubmed-72883102020-06-17 Association of Body Mass Index and Waist Circumference with All-Cause Mortality in Hemodialysis Patients Kim, Chang Seong Han, Kyung-Do Choi, Hong Sang Bae, Eun Hui Ma, Seong Kwon Kim, Soo Wan J Clin Med Article In this study based on a large nationally representative sample of Korean adults, we investigated the potential associations of the body mass index (BMI) and waist circumference (WC) with mortality in patients undergoing hemodialysis. We obtained the data of 18,699 participants >20 years of age who were followed up with for 4 years and for whom BMI and WC information were available, using a nationally representative dataset from the Korean National Health Insurance System. Patients were stratified into five levels by their baseline BMI and into six levels by their WC (5-cm increments). A total of 4975 deaths occurred during a median follow-up period of 48.2 months. Participants with a higher BMI had a lower mortality rate than those with a lower BMI. In a fully adjusted Cox regression analysis, being overweight and obese was associated with a significantly lower relative risk of all-cause mortality relative to the reference group. Conversely, the mortality rate was higher among participants with a high WC than among those with a low WC. Participants with the highest WC had a higher risk of mortality, while those with the lowest WC level had a significantly lower risk of mortality. In conclusion, all-cause mortality was positively associated with WC, a measure of abdominal obesity, and inversely associated with BMI, a measure of body volume, in patients undergoing hemodialysis. MDPI 2020-04-29 /pmc/articles/PMC7288310/ /pubmed/32365666 http://dx.doi.org/10.3390/jcm9051289 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kim, Chang Seong
Han, Kyung-Do
Choi, Hong Sang
Bae, Eun Hui
Ma, Seong Kwon
Kim, Soo Wan
Association of Body Mass Index and Waist Circumference with All-Cause Mortality in Hemodialysis Patients
title Association of Body Mass Index and Waist Circumference with All-Cause Mortality in Hemodialysis Patients
title_full Association of Body Mass Index and Waist Circumference with All-Cause Mortality in Hemodialysis Patients
title_fullStr Association of Body Mass Index and Waist Circumference with All-Cause Mortality in Hemodialysis Patients
title_full_unstemmed Association of Body Mass Index and Waist Circumference with All-Cause Mortality in Hemodialysis Patients
title_short Association of Body Mass Index and Waist Circumference with All-Cause Mortality in Hemodialysis Patients
title_sort association of body mass index and waist circumference with all-cause mortality in hemodialysis patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288310/
https://www.ncbi.nlm.nih.gov/pubmed/32365666
http://dx.doi.org/10.3390/jcm9051289
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