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FNDC5/irisin improves the therapeutic efficacy of bone marrow-derived mesenchymal stem cells for myocardial infarction
BACKGROUND: The beneficial functions of bone marrow mesenchymal stem cells (BM-MSCs) decline with decreased cell survival, limiting their therapeutic efficacy for myocardial infarction (MI). Irisin, a novel myokine which is cleaved from its precursor fibronectin type III domain-containing protein 5...
Autores principales: | Deng, Jingyu, Zhang, Ning, Wang, Yong, Yang, Chao, Wang, Yabin, Xin, Chao, Zhao, Jinming, Jin, Zhitao, Cao, Feng, Zhang, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288492/ https://www.ncbi.nlm.nih.gov/pubmed/32522253 http://dx.doi.org/10.1186/s13287-020-01746-z |
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