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TRIM2 directly deubiquitinates and stabilizes Snail1 protein, mediating proliferation and metastasis of lung adenocarcinoma

BACKGROUND: Lung adenocarcinoma has surpassed lung squamous cell carcinoma as the most common type of non-small cell lung cancer. In this study, we had tested the biological role of TRIM2 in lung adenocarcinoma. METHODS: TRIM2 abundance in clinical tissues and six cell lines were examined with quant...

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Detalles Bibliográficos
Autores principales:	Lin, Zhaoxian, Lin, Xing, Zhu, Lihuan, Huang, Jianyuan, Huang, Yangyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288537/ https://www.ncbi.nlm.nih.gov/pubmed/32536816 http://dx.doi.org/10.1186/s12935-020-01316-6

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