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A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group

The outbreak of coronavirus disease 2019 (COVID‐19) has rapidly spread globally since being identified as a public health emergency of major international concern and has now been declared a pandemic by the World Health Organization (WHO). In December 2019, an outbreak of atypical pneumonia, known a...

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Autores principales: Al‐Shamsi, Humaid O., Alhazzani, Waleed, Alhuraiji, Ahmad, Coomes, Eric A., Chemaly, Roy F., Almuhanna, Meshari, Wolff, Robert A., Ibrahim, Nuhad K., Chua, Melvin L.K., Hotte, Sebastien J., Meyers, Brandon M., Elfiki, Tarek, Curigliano, Giuseppe, Eng, Cathy, Grothey, Axel, Xie, Conghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288661/
https://www.ncbi.nlm.nih.gov/pubmed/32243668
http://dx.doi.org/10.1634/theoncologist.2020-0213
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author Al‐Shamsi, Humaid O.
Alhazzani, Waleed
Alhuraiji, Ahmad
Coomes, Eric A.
Chemaly, Roy F.
Almuhanna, Meshari
Wolff, Robert A.
Ibrahim, Nuhad K.
Chua, Melvin L.K.
Hotte, Sebastien J.
Meyers, Brandon M.
Elfiki, Tarek
Curigliano, Giuseppe
Eng, Cathy
Grothey, Axel
Xie, Conghua
author_facet Al‐Shamsi, Humaid O.
Alhazzani, Waleed
Alhuraiji, Ahmad
Coomes, Eric A.
Chemaly, Roy F.
Almuhanna, Meshari
Wolff, Robert A.
Ibrahim, Nuhad K.
Chua, Melvin L.K.
Hotte, Sebastien J.
Meyers, Brandon M.
Elfiki, Tarek
Curigliano, Giuseppe
Eng, Cathy
Grothey, Axel
Xie, Conghua
author_sort Al‐Shamsi, Humaid O.
collection PubMed
description The outbreak of coronavirus disease 2019 (COVID‐19) has rapidly spread globally since being identified as a public health emergency of major international concern and has now been declared a pandemic by the World Health Organization (WHO). In December 2019, an outbreak of atypical pneumonia, known as COVID‐19, was identified in Wuhan, China. The newly identified zoonotic coronavirus, severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2), is characterized by rapid human‐to‐human transmission. Many cancer patients frequently visit the hospital for treatment and disease surveillance. They may be immunocompromised due to the underlying malignancy or anticancer therapy and are at higher risk of developing infections. Several factors increase the risk of infection, and cancer patients commonly have multiple risk factors. Cancer patients appear to have an estimated twofold increased risk of contracting SARS‐CoV‐2 than the general population. With the WHO declaring the novel coronavirus outbreak a pandemic, there is an urgent need to address the impact of such a pandemic on cancer patients. This include changes to resource allocation, clinical care, and the consent process during a pandemic. Currently and due to limited data, there are no international guidelines to address the management of cancer patients in any infectious pandemic. In this review, the potential challenges associated with managing cancer patients during the COVID‐19 infection pandemic will be addressed, with suggestions of some practical approaches. IMPLICATIONS FOR PRACTICE: The main management strategies for treating cancer patients during the COVID‐19 epidemic include clear communication and education about hand hygiene, infection control measures, high‐risk exposure, and the signs and symptoms of COVID‐19. Consideration of risk and benefit for active intervention in the cancer population must be individualized. Postponing elective surgery or adjuvant chemotherapy for cancer patients with low risk of progression should be considered on a case‐by‐case basis. Minimizing outpatient visits can help to mitigate exposure and possible further transmission. Telemedicine may be used to support patients to minimize number of visits and risk of exposure. More research is needed to better understand SARS‐CoV‐2 virology and epidemiology.
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spelling pubmed-72886612020-06-12 A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group Al‐Shamsi, Humaid O. Alhazzani, Waleed Alhuraiji, Ahmad Coomes, Eric A. Chemaly, Roy F. Almuhanna, Meshari Wolff, Robert A. Ibrahim, Nuhad K. Chua, Melvin L.K. Hotte, Sebastien J. Meyers, Brandon M. Elfiki, Tarek Curigliano, Giuseppe Eng, Cathy Grothey, Axel Xie, Conghua Oncologist Global Health and Cancer The outbreak of coronavirus disease 2019 (COVID‐19) has rapidly spread globally since being identified as a public health emergency of major international concern and has now been declared a pandemic by the World Health Organization (WHO). In December 2019, an outbreak of atypical pneumonia, known as COVID‐19, was identified in Wuhan, China. The newly identified zoonotic coronavirus, severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2), is characterized by rapid human‐to‐human transmission. Many cancer patients frequently visit the hospital for treatment and disease surveillance. They may be immunocompromised due to the underlying malignancy or anticancer therapy and are at higher risk of developing infections. Several factors increase the risk of infection, and cancer patients commonly have multiple risk factors. Cancer patients appear to have an estimated twofold increased risk of contracting SARS‐CoV‐2 than the general population. With the WHO declaring the novel coronavirus outbreak a pandemic, there is an urgent need to address the impact of such a pandemic on cancer patients. This include changes to resource allocation, clinical care, and the consent process during a pandemic. Currently and due to limited data, there are no international guidelines to address the management of cancer patients in any infectious pandemic. In this review, the potential challenges associated with managing cancer patients during the COVID‐19 infection pandemic will be addressed, with suggestions of some practical approaches. IMPLICATIONS FOR PRACTICE: The main management strategies for treating cancer patients during the COVID‐19 epidemic include clear communication and education about hand hygiene, infection control measures, high‐risk exposure, and the signs and symptoms of COVID‐19. Consideration of risk and benefit for active intervention in the cancer population must be individualized. Postponing elective surgery or adjuvant chemotherapy for cancer patients with low risk of progression should be considered on a case‐by‐case basis. Minimizing outpatient visits can help to mitigate exposure and possible further transmission. Telemedicine may be used to support patients to minimize number of visits and risk of exposure. More research is needed to better understand SARS‐CoV‐2 virology and epidemiology. John Wiley & Sons, Inc. 2020-04-27 2020-06 /pmc/articles/PMC7288661/ /pubmed/32243668 http://dx.doi.org/10.1634/theoncologist.2020-0213 Text en © 2020 The Authors. The Oncologist published by Wiley Periodicals, Inc. on behalf of AlphaMed Press. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Global Health and Cancer
Al‐Shamsi, Humaid O.
Alhazzani, Waleed
Alhuraiji, Ahmad
Coomes, Eric A.
Chemaly, Roy F.
Almuhanna, Meshari
Wolff, Robert A.
Ibrahim, Nuhad K.
Chua, Melvin L.K.
Hotte, Sebastien J.
Meyers, Brandon M.
Elfiki, Tarek
Curigliano, Giuseppe
Eng, Cathy
Grothey, Axel
Xie, Conghua
A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group
title A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group
title_full A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group
title_fullStr A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group
title_full_unstemmed A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group
title_short A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group
title_sort practical approach to the management of cancer patients during the novel coronavirus disease 2019 (covid‐19) pandemic: an international collaborative group
topic Global Health and Cancer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288661/
https://www.ncbi.nlm.nih.gov/pubmed/32243668
http://dx.doi.org/10.1634/theoncologist.2020-0213
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