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Laboratory Limitations of Excluding Hereditary Protein C Deficiency by Chromogenic Assay: Discrepancies of Phenotype and Genotype

Protein C (PC) deficiency is associated with an increased risk for venous thromboembolism (VTE). In daily practice, exclusion of a hereditary PC deficiency is often based on a single determination of PC activity, by either clotting time–based or mostly chromogenic assay. However, diagnosis of heredi...

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Detalles Bibliográficos
Autores principales: Seidel, Holger, Haracska, Bianca, Naumann, Jennifer, Westhofen, Philipp, Hass, Moritz Sebastian, Kruppenbacher, Johannes Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288809/
https://www.ncbi.nlm.nih.gov/pubmed/32309994
http://dx.doi.org/10.1177/1076029620912028