Gorlin syndrome-induced pluripotent stem cells form medulloblastoma with loss of heterozygosity in PTCH1

Gorlin syndrome is a rare autosomal dominant hereditary disease with a high incidence of tumors such as basal cell carcinoma and medulloblastoma. Disease-specific induced pluripotent stem cells (iPSCs) and an animal model have been used to analyze disease pathogenesis. In this study, we generated iP...

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Detalles Bibliográficos
Autores principales: Ikemoto, Yu, Miyashita, Toshiyuki, Nasu, Michiyo, Hatsuse, Hiromi, Kajiwara, Kazuhiro, Fujii, Katsunori, Motojima, Toshino, Kokido, Ibuki, Toyoda, Masashi, Umezawa, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288908/
https://www.ncbi.nlm.nih.gov/pubmed/32436863
http://dx.doi.org/10.18632/aging.103258

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