Loss of macroH2A1 decreases mitochondrial metabolism and reduces the aggressiveness of uveal melanoma cells

Uveal melanoma (UM) is the most common primary intraocular tumour in adults. The most accurate prognostic factor of UM is classification by gene expression profiling. Currently, the role of epigenetics is much less defined compared to genetic mechanisms. We recently showed a strong prognostic role o...

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Detalles Bibliográficos
Autores principales: Giallongo, Sebastiano, Di Rosa, Michelino, Caltabiano, Rosario, Longhitano, Lucia, Reibaldi, Michele, Distefano, Alfio, Lo Re, Oriana, Amorini, Angela Maria, Puzzo, Lidia, Salvatorelli, Lucia, Palmucci, Stefano, Tibullo, Daniele, Russo, Andrea, Longo, Antonio, Lazzarino, Giacomo, Li Volti, Giovanni, Vinciguerra, Manlio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288915/
https://www.ncbi.nlm.nih.gov/pubmed/32401230
http://dx.doi.org/10.18632/aging.103241

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