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Topoisomerase II-binding protein 1 promotes the progression of prostate cancer via ATR-CHK1 signaling pathway

DNA damage response (DDR) plays an important role in the progression of cancers, including prostate cancer (PCa). Topoisomerase II-binding protein 1 (TopBP1) is an essential promotor of ATR-mediated DDR. Herein, we investigated the association between TopBP1 and PCa and determined its effect on the...

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Detalles Bibliográficos
Autores principales:	Li, Kaiwen, Peng, Shirong, Li, Zean, Lai, Yiming, Wang, Qiong, Tao, Yiran, Wu, Wanhua, Zhou, Qianghua, Gao, Ze, Chen, Junxiu, Li, Hui, Cai, Wenli, Guo, Zhenghui, Huang, Hai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288942/ https://www.ncbi.nlm.nih.gov/pubmed/32459662 http://dx.doi.org/10.18632/aging.103260

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