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Amphiregulin promotes cisplatin chemoresistance by upregulating ABCB1 expression in human chondrosarcoma

Chondrosarcomas are well known for their resistance to chemotherapeutic agents, including cisplatin, which is commonly used in chondrosarcomas. Amphiregulin (AR), a ligand of epidermal growth factor receptor (EGFR), plays an important role in drug resistance. We therefore sought to determine the rol...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Wen, Lin, Chih-Yang, Tsai, Hsiao-Chi, Fong, Yi-Chin, Han, Chien-Kuo, Huang, Yuan-Li, Wu, Wen-Tung, Cheng, Shih-Ping, Chang, Hao-Chiun, Liao, Kuang-Wen, Wang, Shih-Wei, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288968/
https://www.ncbi.nlm.nih.gov/pubmed/32428872
http://dx.doi.org/10.18632/aging.103220