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Suberoylanilide hydroxamic acid overcomes erlotinib-acquired resistance via phosphatase and tensin homolog deleted on chromosome 10-mediated apoptosis in non-small cell lung cancer

BACKGROUND: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), such as erlotinib and gefitinib, are widely used to treat non-small cell lung cancer (NSCLC). However, acquired resistance is unavoidable, impairing the anti-tumor effects of EGFR-TKIs. It is reported that histone...

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Detalles Bibliográficos
Autores principales:	Wu, Peng-Fei, Gao, Wei-Wei, Sun, Cui-Lan, Ma, Tai, Hao, Ji-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289310/ https://www.ncbi.nlm.nih.gov/pubmed/32452893 http://dx.doi.org/10.1097/CM9.0000000000000823

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