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Adaptation of codon usage to tRNA I34 modification controls translation kinetics and proteome landscape

Codon usage bias is a universal feature of all genomes and plays an important role in regulating protein expression levels. Modification of adenosine to inosine at the tRNA anticodon wobble position (I34) by adenosine deaminases (ADATs) is observed in all eukaryotes and has been proposed to explain...

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Detalles Bibliográficos
Autores principales: Lyu, Xueliang, Yang, Qian, Li, Lin, Dang, Yunkun, Zhou, Zhipeng, Chen, She, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289440/
https://www.ncbi.nlm.nih.gov/pubmed/32479508
http://dx.doi.org/10.1371/journal.pgen.1008836