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Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics

A variety of different signals induce specific responses through a common, extracellular-signal regulated kinase (ERK)-dependent cascade. It has been suggested that signaling specificity can be achieved through precise temporal regulation of ERK activity. Given the wide distrubtion of ERK susbtrates...

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Detalles Bibliográficos
Autores principales:	Keyes, Jeremiah, Ganesan, Ambhighainath, Molinar-Inglis, Olivia, Hamidzadeh, Archer, Zhang, Jinfan, Ling, Megan, Trejo, JoAnn, Levchenko, Andre, Zhang, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289600/ https://www.ncbi.nlm.nih.gov/pubmed/32452765 http://dx.doi.org/10.7554/eLife.57410

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