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Assessment of a Deep Learning Algorithm for the Detection of Rib Fractures on Whole-Body Trauma Computed Tomography
OBJECTIVE: To assess the diagnostic performance of a deep learning-based algorithm for automated detection of acute and chronic rib fractures on whole-body trauma CT. MATERIALS AND METHODS: We retrospectively identified all whole-body trauma CT scans referred from the emergency department of our hos...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Radiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289702/ https://www.ncbi.nlm.nih.gov/pubmed/32524789 http://dx.doi.org/10.3348/kjr.2019.0653 |
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author | Weikert, Thomas Noordtzij, Luca Andre Bremerich, Jens Stieltjes, Bram Parmar, Victor Cyriac, Joshy Sommer, Gregor Sauter, Alexander Walter |
author_facet | Weikert, Thomas Noordtzij, Luca Andre Bremerich, Jens Stieltjes, Bram Parmar, Victor Cyriac, Joshy Sommer, Gregor Sauter, Alexander Walter |
author_sort | Weikert, Thomas |
collection | PubMed |
description | OBJECTIVE: To assess the diagnostic performance of a deep learning-based algorithm for automated detection of acute and chronic rib fractures on whole-body trauma CT. MATERIALS AND METHODS: We retrospectively identified all whole-body trauma CT scans referred from the emergency department of our hospital from January to December 2018 (n = 511). Scans were categorized as positive (n = 159) or negative (n = 352) for rib fractures according to the clinically approved written CT reports, which served as the index test. The bone kernel series (1.5-mm slice thickness) served as an input for a detection prototype algorithm trained to detect both acute and chronic rib fractures based on a deep convolutional neural network. It had previously been trained on an independent sample from eight other institutions (n = 11455). RESULTS: All CTs except one were successfully processed (510/511). The algorithm achieved a sensitivity of 87.4% and specificity of 91.5% on a per-examination level [per CT scan: rib fracture(s): yes/no]. There were 0.16 false-positives per examination (= 81/510). On a per-finding level, there were 587 true-positive findings (sensitivity: 65.7%) and 307 false-negatives. Furthermore, 97 true rib fractures were detected that were not mentioned in the written CT reports. A major factor associated with correct detection was displacement. CONCLUSION: We found good performance of a deep learning-based prototype algorithm detecting rib fractures on trauma CT on a per-examination level at a low rate of false-positives per case. A potential area for clinical application is its use as a screening tool to avoid false-negative radiology reports. |
format | Online Article Text |
id | pubmed-7289702 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Korean Society of Radiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-72897022020-07-01 Assessment of a Deep Learning Algorithm for the Detection of Rib Fractures on Whole-Body Trauma Computed Tomography Weikert, Thomas Noordtzij, Luca Andre Bremerich, Jens Stieltjes, Bram Parmar, Victor Cyriac, Joshy Sommer, Gregor Sauter, Alexander Walter Korean J Radiol Thoracic Imaging OBJECTIVE: To assess the diagnostic performance of a deep learning-based algorithm for automated detection of acute and chronic rib fractures on whole-body trauma CT. MATERIALS AND METHODS: We retrospectively identified all whole-body trauma CT scans referred from the emergency department of our hospital from January to December 2018 (n = 511). Scans were categorized as positive (n = 159) or negative (n = 352) for rib fractures according to the clinically approved written CT reports, which served as the index test. The bone kernel series (1.5-mm slice thickness) served as an input for a detection prototype algorithm trained to detect both acute and chronic rib fractures based on a deep convolutional neural network. It had previously been trained on an independent sample from eight other institutions (n = 11455). RESULTS: All CTs except one were successfully processed (510/511). The algorithm achieved a sensitivity of 87.4% and specificity of 91.5% on a per-examination level [per CT scan: rib fracture(s): yes/no]. There were 0.16 false-positives per examination (= 81/510). On a per-finding level, there were 587 true-positive findings (sensitivity: 65.7%) and 307 false-negatives. Furthermore, 97 true rib fractures were detected that were not mentioned in the written CT reports. A major factor associated with correct detection was displacement. CONCLUSION: We found good performance of a deep learning-based prototype algorithm detecting rib fractures on trauma CT on a per-examination level at a low rate of false-positives per case. A potential area for clinical application is its use as a screening tool to avoid false-negative radiology reports. The Korean Society of Radiology 2020-07 2019-06-05 /pmc/articles/PMC7289702/ /pubmed/32524789 http://dx.doi.org/10.3348/kjr.2019.0653 Text en Copyright © 2020 The Korean Society of Radiology http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Thoracic Imaging Weikert, Thomas Noordtzij, Luca Andre Bremerich, Jens Stieltjes, Bram Parmar, Victor Cyriac, Joshy Sommer, Gregor Sauter, Alexander Walter Assessment of a Deep Learning Algorithm for the Detection of Rib Fractures on Whole-Body Trauma Computed Tomography |
title | Assessment of a Deep Learning Algorithm for the Detection of Rib Fractures on Whole-Body Trauma Computed Tomography |
title_full | Assessment of a Deep Learning Algorithm for the Detection of Rib Fractures on Whole-Body Trauma Computed Tomography |
title_fullStr | Assessment of a Deep Learning Algorithm for the Detection of Rib Fractures on Whole-Body Trauma Computed Tomography |
title_full_unstemmed | Assessment of a Deep Learning Algorithm for the Detection of Rib Fractures on Whole-Body Trauma Computed Tomography |
title_short | Assessment of a Deep Learning Algorithm for the Detection of Rib Fractures on Whole-Body Trauma Computed Tomography |
title_sort | assessment of a deep learning algorithm for the detection of rib fractures on whole-body trauma computed tomography |
topic | Thoracic Imaging |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289702/ https://www.ncbi.nlm.nih.gov/pubmed/32524789 http://dx.doi.org/10.3348/kjr.2019.0653 |
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