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Multiple assays in a real-time RT-PCR SARS-CoV-2 panel can mitigate the risk of loss of sensitivity by new genomic variants during the COVID-19 outbreak

OBJECTIVES: In this study, five SARS-CoV-2 PCR assay panels were evaluated against the accumulated genetic variability of the virus to assess the effect on sensitivity of the individual assays. DESIGN OR METHODS: As of week 21, 2020, the complete set of available SARS-CoV-2 genomes from GISAID and G...

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Detalles Bibliográficos
Autores principales: Peñarrubia, Luis, Ruiz, Maria, Porco, Roberto, Rao, Sonia N., Juanola-Falgarona, Martí, Manissero, Davide, López-Fontanals, Marta, Pareja, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289722/
https://www.ncbi.nlm.nih.gov/pubmed/32535302
http://dx.doi.org/10.1016/j.ijid.2020.06.027

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