Linking key intervention timing to rapid decline of the COVID-19 effective reproductive number to quantify lessons from mainland China

Effective reproductive numbers (R(t)) were calculated from data on the COVID-19 outbreak in China and linked to dates in 2020 when different interventions were enacted. From a maximum of 3.98 before the lockdown in Wuhan City, the values of R(t) declined to below 1 by the second week of February, af...

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Autores principales: Xiao, Yanni, Tang, Biao, Wu, Jianhong, Cheke, Robert A., Tang, Sanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289726/
https://www.ncbi.nlm.nih.gov/pubmed/32535298
http://dx.doi.org/10.1016/j.ijid.2020.06.030
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author Xiao, Yanni
Tang, Biao
Wu, Jianhong
Cheke, Robert A.
Tang, Sanyi
author_facet Xiao, Yanni
Tang, Biao
Wu, Jianhong
Cheke, Robert A.
Tang, Sanyi
author_sort Xiao, Yanni
collection PubMed
description Effective reproductive numbers (R(t)) were calculated from data on the COVID-19 outbreak in China and linked to dates in 2020 when different interventions were enacted. From a maximum of 3.98 before the lockdown in Wuhan City, the values of R(t) declined to below 1 by the second week of February, after the construction of hospitals dedicated to COVID-19 patients. The R(t) continued to decline following additional measures in line with the policy of “early detection, early report, early quarantine, and early treatment.” The results provide quantitative evaluations of how intervention measures and their timings succeeded, from which lessons can be learned by other countries dealing with future outbreaks.
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spelling pubmed-72897262020-06-12 Linking key intervention timing to rapid decline of the COVID-19 effective reproductive number to quantify lessons from mainland China Xiao, Yanni Tang, Biao Wu, Jianhong Cheke, Robert A. Tang, Sanyi Int J Infect Dis Article Effective reproductive numbers (R(t)) were calculated from data on the COVID-19 outbreak in China and linked to dates in 2020 when different interventions were enacted. From a maximum of 3.98 before the lockdown in Wuhan City, the values of R(t) declined to below 1 by the second week of February, after the construction of hospitals dedicated to COVID-19 patients. The R(t) continued to decline following additional measures in line with the policy of “early detection, early report, early quarantine, and early treatment.” The results provide quantitative evaluations of how intervention measures and their timings succeeded, from which lessons can be learned by other countries dealing with future outbreaks. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020-08 2020-06-12 /pmc/articles/PMC7289726/ /pubmed/32535298 http://dx.doi.org/10.1016/j.ijid.2020.06.030 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Xiao, Yanni
Tang, Biao
Wu, Jianhong
Cheke, Robert A.
Tang, Sanyi
Linking key intervention timing to rapid decline of the COVID-19 effective reproductive number to quantify lessons from mainland China
title Linking key intervention timing to rapid decline of the COVID-19 effective reproductive number to quantify lessons from mainland China
title_full Linking key intervention timing to rapid decline of the COVID-19 effective reproductive number to quantify lessons from mainland China
title_fullStr Linking key intervention timing to rapid decline of the COVID-19 effective reproductive number to quantify lessons from mainland China
title_full_unstemmed Linking key intervention timing to rapid decline of the COVID-19 effective reproductive number to quantify lessons from mainland China
title_short Linking key intervention timing to rapid decline of the COVID-19 effective reproductive number to quantify lessons from mainland China
title_sort linking key intervention timing to rapid decline of the covid-19 effective reproductive number to quantify lessons from mainland china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289726/
https://www.ncbi.nlm.nih.gov/pubmed/32535298
http://dx.doi.org/10.1016/j.ijid.2020.06.030
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