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Fight against novel coronavirus: A perspective of medicinal chemists

The ongoing novel coronavirus disease (COVID-19) pandemic makes us painfully perceive that our bullet shells are blank so far for fighting against severe human coronavirus (HCoV). In spite of vast research work, it is crystal clear that the evident does not warrant the commercial blossoming of anti-...

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Detalles Bibliográficos
Autores principales: Amin, Sk Abdul, Jha, Tarun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289749/
https://www.ncbi.nlm.nih.gov/pubmed/32563814
http://dx.doi.org/10.1016/j.ejmech.2020.112559
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author Amin, Sk Abdul
Jha, Tarun
author_facet Amin, Sk Abdul
Jha, Tarun
author_sort Amin, Sk Abdul
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description The ongoing novel coronavirus disease (COVID-19) pandemic makes us painfully perceive that our bullet shells are blank so far for fighting against severe human coronavirus (HCoV). In spite of vast research work, it is crystal clear that the evident does not warrant the commercial blossoming of anti-HCoV drugs. In this circumstance, drug repurposing and/or screening of databases are the only fastest option. This study is an initiative to recapitulate the medicinal chemistry of severe acute respiratory syndrome (SARS)-CoV-2 (SARS-CoV-2). The aim is to present an exquisite delineation of the current research from the perspective of a medicinal chemist to allow the rapid development of anti-SARS-CoV-2 agents.
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spelling pubmed-72897492020-06-12 Fight against novel coronavirus: A perspective of medicinal chemists Amin, Sk Abdul Jha, Tarun Eur J Med Chem Review Article The ongoing novel coronavirus disease (COVID-19) pandemic makes us painfully perceive that our bullet shells are blank so far for fighting against severe human coronavirus (HCoV). In spite of vast research work, it is crystal clear that the evident does not warrant the commercial blossoming of anti-HCoV drugs. In this circumstance, drug repurposing and/or screening of databases are the only fastest option. This study is an initiative to recapitulate the medicinal chemistry of severe acute respiratory syndrome (SARS)-CoV-2 (SARS-CoV-2). The aim is to present an exquisite delineation of the current research from the perspective of a medicinal chemist to allow the rapid development of anti-SARS-CoV-2 agents. Elsevier Masson SAS. 2020-09-01 2020-06-12 /pmc/articles/PMC7289749/ /pubmed/32563814 http://dx.doi.org/10.1016/j.ejmech.2020.112559 Text en © 2020 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review Article
Amin, Sk Abdul
Jha, Tarun
Fight against novel coronavirus: A perspective of medicinal chemists
title Fight against novel coronavirus: A perspective of medicinal chemists
title_full Fight against novel coronavirus: A perspective of medicinal chemists
title_fullStr Fight against novel coronavirus: A perspective of medicinal chemists
title_full_unstemmed Fight against novel coronavirus: A perspective of medicinal chemists
title_short Fight against novel coronavirus: A perspective of medicinal chemists
title_sort fight against novel coronavirus: a perspective of medicinal chemists
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289749/
https://www.ncbi.nlm.nih.gov/pubmed/32563814
http://dx.doi.org/10.1016/j.ejmech.2020.112559
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