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Fight against novel coronavirus: A perspective of medicinal chemists
The ongoing novel coronavirus disease (COVID-19) pandemic makes us painfully perceive that our bullet shells are blank so far for fighting against severe human coronavirus (HCoV). In spite of vast research work, it is crystal clear that the evident does not warrant the commercial blossoming of anti-...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Masson SAS.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289749/ https://www.ncbi.nlm.nih.gov/pubmed/32563814 http://dx.doi.org/10.1016/j.ejmech.2020.112559 |
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author | Amin, Sk Abdul Jha, Tarun |
author_facet | Amin, Sk Abdul Jha, Tarun |
author_sort | Amin, Sk Abdul |
collection | PubMed |
description | The ongoing novel coronavirus disease (COVID-19) pandemic makes us painfully perceive that our bullet shells are blank so far for fighting against severe human coronavirus (HCoV). In spite of vast research work, it is crystal clear that the evident does not warrant the commercial blossoming of anti-HCoV drugs. In this circumstance, drug repurposing and/or screening of databases are the only fastest option. This study is an initiative to recapitulate the medicinal chemistry of severe acute respiratory syndrome (SARS)-CoV-2 (SARS-CoV-2). The aim is to present an exquisite delineation of the current research from the perspective of a medicinal chemist to allow the rapid development of anti-SARS-CoV-2 agents. |
format | Online Article Text |
id | pubmed-7289749 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier Masson SAS. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72897492020-06-12 Fight against novel coronavirus: A perspective of medicinal chemists Amin, Sk Abdul Jha, Tarun Eur J Med Chem Review Article The ongoing novel coronavirus disease (COVID-19) pandemic makes us painfully perceive that our bullet shells are blank so far for fighting against severe human coronavirus (HCoV). In spite of vast research work, it is crystal clear that the evident does not warrant the commercial blossoming of anti-HCoV drugs. In this circumstance, drug repurposing and/or screening of databases are the only fastest option. This study is an initiative to recapitulate the medicinal chemistry of severe acute respiratory syndrome (SARS)-CoV-2 (SARS-CoV-2). The aim is to present an exquisite delineation of the current research from the perspective of a medicinal chemist to allow the rapid development of anti-SARS-CoV-2 agents. Elsevier Masson SAS. 2020-09-01 2020-06-12 /pmc/articles/PMC7289749/ /pubmed/32563814 http://dx.doi.org/10.1016/j.ejmech.2020.112559 Text en © 2020 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Article Amin, Sk Abdul Jha, Tarun Fight against novel coronavirus: A perspective of medicinal chemists |
title | Fight against novel coronavirus: A perspective of medicinal chemists |
title_full | Fight against novel coronavirus: A perspective of medicinal chemists |
title_fullStr | Fight against novel coronavirus: A perspective of medicinal chemists |
title_full_unstemmed | Fight against novel coronavirus: A perspective of medicinal chemists |
title_short | Fight against novel coronavirus: A perspective of medicinal chemists |
title_sort | fight against novel coronavirus: a perspective of medicinal chemists |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289749/ https://www.ncbi.nlm.nih.gov/pubmed/32563814 http://dx.doi.org/10.1016/j.ejmech.2020.112559 |
work_keys_str_mv | AT aminskabdul fightagainstnovelcoronavirusaperspectiveofmedicinalchemists AT jhatarun fightagainstnovelcoronavirusaperspectiveofmedicinalchemists |