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Integrated transcriptomic and genomic analysis improves prediction of complete remission and survival in elderly patients with acute myeloid leukemia

Relevant molecular tools for treatment stratification of patients ≥65 years with acute myeloid leukemia (AML) are lacking. We combined clinical data with targeted DNA- and full RNA-sequencing of 182 intensively and palliatively treated patients to predict complete remission (CR) and survival in AML...

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Detalles Bibliográficos
Autores principales: Österroos, Albin, Björklund, My, Eriksson, Anna, Lindberg, Johan, Nilsson, Christer, Mareschal, Sylvain, Rantalainen, Mattias, Grönberg, Henrik, Lehmann, Sören
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289793/
https://www.ncbi.nlm.nih.gov/pubmed/32527994
http://dx.doi.org/10.1038/s41408-020-0332-3