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A Novel Aβ(40) Assembly at Physiological Concentration

Aggregates of amyloid-β (Aβ) are characteristic of Alzheimer’s disease, but there is no consensus as to either the nature of the toxic molecular complex or the mechanism by which toxic aggregates are produced. We report on a novel feature of amyloid-lipid interactions where discontinuities in the li...

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Detalles Bibliográficos
Autores principales: Tahirbegi, Bogachan, Magness, Alastair J., Piersimoni, Maria Elena, Knöpfel, Thomas, Willison, Keith R., Klug, David R., Ying, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289798/
https://www.ncbi.nlm.nih.gov/pubmed/32528074
http://dx.doi.org/10.1038/s41598-020-66373-3