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Topical application of endothelin receptor a antagonist attenuates imiquimod-induced psoriasiform skin inflammation
Endothelin-1 (ET-1) is well known as the most potent vasoconstrictor, and can evoke histamine-independent pruritus. Recently, its involvement in cutaneous inflammation has begun to draw attention. The upregulation of ET-1 expression in the epidermis of human psoriasis patients has been reported. It...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289852/ https://www.ncbi.nlm.nih.gov/pubmed/32528072 http://dx.doi.org/10.1038/s41598-020-66490-z |