Real-time tracking reveals catalytic roles for the two DNA binding sites of Rad51

During homologous recombination, Rad51 forms a nucleoprotein filament on single-stranded DNA to promote DNA strand exchange. This filament binds to double-stranded DNA (dsDNA), searches for homology, and promotes transfer of the complementary strand, producing a new heteroduplex. Strand exchange pro...

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Detalles Bibliográficos
Autores principales: Ito, Kentaro, Murayama, Yasuto, Kurokawa, Yumiko, Kanamaru, Shuji, Kokabu, Yuichi, Maki, Takahisa, Mikawa, Tsutomu, Argunhan, Bilge, Tsubouchi, Hideo, Ikeguchi, Mitsunori, Takahashi, Masayuki, Iwasaki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289862/
https://www.ncbi.nlm.nih.gov/pubmed/32528002
http://dx.doi.org/10.1038/s41467-020-16750-3

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