Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury

Coronary heart disease is a leading cause of death. Tissue remodeling and fibrosis results in cardiac pump dysfunction and ischemic heart failure. Cardiac fibroblasts may rebuild damaged tissues when prompted by suitable environmental cues. Here, we use acellular biologic extracellular matrix scaffo...

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Detalles Bibliográficos
Autores principales: Svystonyuk, Daniyil A., Mewhort, Holly E. M., Hassanabad, Ali Fatehi, Heydari, Bobak, Mikami, Yoko, Turnbull, Jeannine D., Teng, Guoqi, Belke, Darrell D., Wagner, Karl T., Tarraf, Samar A., DiMartino, Elena S., White, James A., Flewitt, Jacqueline A., Cheung, Matthew, Guzzardi, David G., Kang, Sean, Fedak, Paul W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289874/
https://www.ncbi.nlm.nih.gov/pubmed/32528051
http://dx.doi.org/10.1038/s41598-020-66327-9

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