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Population Pharmacokinetics and Limited Sampling Strategy for Therapeutic Drug Monitoring of Polymyxin B in Chinese Patients With Multidrug-Resistant Gram-Negative Bacterial Infections

Polymyxin B is used as a last therapeutic option for the treatment of multidrug-resistant Gram-negative bacterial infections. This study aimed to develop a population pharmacokinetic model and limited sampling strategy, a method to estimate the area under the concentration curve (AUC) by using a lim...

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Detalles Bibliográficos
Autores principales:	Wang, Peile, Zhang, Qiwen, Zhu, Zhenfeng, Feng, Min, Sun, Tongwen, Yang, Jing, Zhang, Xiaojian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289991/ https://www.ncbi.nlm.nih.gov/pubmed/32581795 http://dx.doi.org/10.3389/fphar.2020.00829

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