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Evaluation of T-Cell Responses Against Shared Melanoma Associated Antigens and Predicted Neoantigens in Cutaneous Melanoma Patients Treated With the CSF-470 Allogeneic Cell Vaccine Plus BCG and GM-CSF
The CSF-470 vaccine consists of lethally-irradiated allogeneic cells derived from four cutaneous melanoma cell lines administered plus BCG and GM-CSF as adjuvants. In an adjuvant phase II study vs. IFN-α2b, the vaccine significantly prolonged the distant metastasis-free survival (DMFS) of stages IIB...
Autores principales: | Podaza, Enrique, Carri, Ibel, Aris, Mariana, von Euw, Erika, Bravo, Alicia Inés, Blanco, Paula, Ortiz Wilczyñski, Juan Manuel, Koile, Daniel, Yankilevich, Patricio, Nielsen, Morten, Mordoh, José, Barrio, María Marcela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290006/ https://www.ncbi.nlm.nih.gov/pubmed/32582212 http://dx.doi.org/10.3389/fimmu.2020.01147 |
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