Cargando…
Applications of Machine Learning in miRNA Discovery and Target Prediction
MicroRNA (miRNA) is a small non-coding molecule that is involved in gene regulation and RNA silencing by complementary on their targets. Experimental methods for target prediction can be time-consuming and expensive. Thus, the application of the computational approach is implicated to enlighten thes...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290058/ https://www.ncbi.nlm.nih.gov/pubmed/32581642 http://dx.doi.org/10.2174/1389202921666200106111813 |
_version_ | 1783545590749069312 |
---|---|
author | Parveen, Alisha Mustafa, Syed H. Yadav, Pankaj Kumar, Abhishek |
author_facet | Parveen, Alisha Mustafa, Syed H. Yadav, Pankaj Kumar, Abhishek |
author_sort | Parveen, Alisha |
collection | PubMed |
description | MicroRNA (miRNA) is a small non-coding molecule that is involved in gene regulation and RNA silencing by complementary on their targets. Experimental methods for target prediction can be time-consuming and expensive. Thus, the application of the computational approach is implicated to enlighten these complications with experimental studies. However, there is still a need for an optimized approach in miRNA biology. Therefore, machine learning (ML) would initiate a new era of research in miRNA biology towards potential diseases biomarker. In this article, we described the application of ML approaches in miRNA discovery and target prediction with functions and future prospective. The implementation of a new era of computational methodologies in this direction would initiate further advanced levels of discoveries in miRNA. |
format | Online Article Text |
id | pubmed-7290058 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Bentham Science Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-72900582020-06-23 Applications of Machine Learning in miRNA Discovery and Target Prediction Parveen, Alisha Mustafa, Syed H. Yadav, Pankaj Kumar, Abhishek Curr Genomics Article MicroRNA (miRNA) is a small non-coding molecule that is involved in gene regulation and RNA silencing by complementary on their targets. Experimental methods for target prediction can be time-consuming and expensive. Thus, the application of the computational approach is implicated to enlighten these complications with experimental studies. However, there is still a need for an optimized approach in miRNA biology. Therefore, machine learning (ML) would initiate a new era of research in miRNA biology towards potential diseases biomarker. In this article, we described the application of ML approaches in miRNA discovery and target prediction with functions and future prospective. The implementation of a new era of computational methodologies in this direction would initiate further advanced levels of discoveries in miRNA. Bentham Science Publishers 2019-12 2019-12 /pmc/articles/PMC7290058/ /pubmed/32581642 http://dx.doi.org/10.2174/1389202921666200106111813 Text en © 2019 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Parveen, Alisha Mustafa, Syed H. Yadav, Pankaj Kumar, Abhishek Applications of Machine Learning in miRNA Discovery and Target Prediction |
title | Applications of Machine Learning in miRNA Discovery and Target Prediction |
title_full | Applications of Machine Learning in miRNA Discovery and Target Prediction |
title_fullStr | Applications of Machine Learning in miRNA Discovery and Target Prediction |
title_full_unstemmed | Applications of Machine Learning in miRNA Discovery and Target Prediction |
title_short | Applications of Machine Learning in miRNA Discovery and Target Prediction |
title_sort | applications of machine learning in mirna discovery and target prediction |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290058/ https://www.ncbi.nlm.nih.gov/pubmed/32581642 http://dx.doi.org/10.2174/1389202921666200106111813 |
work_keys_str_mv | AT parveenalisha applicationsofmachinelearninginmirnadiscoveryandtargetprediction AT mustafasyedh applicationsofmachinelearninginmirnadiscoveryandtargetprediction AT yadavpankaj applicationsofmachinelearninginmirnadiscoveryandtargetprediction AT kumarabhishek applicationsofmachinelearninginmirnadiscoveryandtargetprediction |