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Agonist bias and agonist‐dependent antagonism at corticotrophin releasing factor receptors

The corticotropin‐releasing factor (CRF) receptors represent potential drug targets for the treatment of anxiety, stress, and other disorders. However, it is not known if endogenous CRF receptor agonists display biased signaling, how effective CRF receptor antagonists are at blocking different agoni...

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Detalles Bibliográficos
Autores principales: Tasma, Zoe, Wills, Peter, Hay, Debbie L., Walker, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290078/
https://www.ncbi.nlm.nih.gov/pubmed/32529807
http://dx.doi.org/10.1002/prp2.595