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Prostate Cancer Theranostics - An Overview

Metastatic prostate cancer is incurable, and novel methods to detect the disease earlier and to direct definitive treatment are needed. Molecularly specific tools to localize diagnostic and cytotoxic radionuclide payloads to cancer cells and the surrounding microenvironment are recognized as a criti...

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Autores principales: Abou, Diane, Benabdallah, Nadia, Jiang, Wen, Peng, Lu, Zhang, Hanwen, Villmer, Alexandria, Longtine, Mark S., Thorek, Daniel L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290246/
https://www.ncbi.nlm.nih.gov/pubmed/32582550
http://dx.doi.org/10.3389/fonc.2020.00884
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author Abou, Diane
Benabdallah, Nadia
Jiang, Wen
Peng, Lu
Zhang, Hanwen
Villmer, Alexandria
Longtine, Mark S.
Thorek, Daniel L. J.
author_facet Abou, Diane
Benabdallah, Nadia
Jiang, Wen
Peng, Lu
Zhang, Hanwen
Villmer, Alexandria
Longtine, Mark S.
Thorek, Daniel L. J.
author_sort Abou, Diane
collection PubMed
description Metastatic prostate cancer is incurable, and novel methods to detect the disease earlier and to direct definitive treatment are needed. Molecularly specific tools to localize diagnostic and cytotoxic radionuclide payloads to cancer cells and the surrounding microenvironment are recognized as a critical component of new approaches to combat this disease. The implementation of theranostic approaches to characterize and personalize patient management is beginning to be realized for prostate cancer patients. This review article summarized clinically translated approaches to detect, characterize, and treat disease in this rapidly expanding field.
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spelling pubmed-72902462020-06-23 Prostate Cancer Theranostics - An Overview Abou, Diane Benabdallah, Nadia Jiang, Wen Peng, Lu Zhang, Hanwen Villmer, Alexandria Longtine, Mark S. Thorek, Daniel L. J. Front Oncol Oncology Metastatic prostate cancer is incurable, and novel methods to detect the disease earlier and to direct definitive treatment are needed. Molecularly specific tools to localize diagnostic and cytotoxic radionuclide payloads to cancer cells and the surrounding microenvironment are recognized as a critical component of new approaches to combat this disease. The implementation of theranostic approaches to characterize and personalize patient management is beginning to be realized for prostate cancer patients. This review article summarized clinically translated approaches to detect, characterize, and treat disease in this rapidly expanding field. Frontiers Media S.A. 2020-06-05 /pmc/articles/PMC7290246/ /pubmed/32582550 http://dx.doi.org/10.3389/fonc.2020.00884 Text en Copyright © 2020 Abou, Benabdallah, Jiang, Peng, Zhang, Villmer, Longtine and Thorek. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Abou, Diane
Benabdallah, Nadia
Jiang, Wen
Peng, Lu
Zhang, Hanwen
Villmer, Alexandria
Longtine, Mark S.
Thorek, Daniel L. J.
Prostate Cancer Theranostics - An Overview
title Prostate Cancer Theranostics - An Overview
title_full Prostate Cancer Theranostics - An Overview
title_fullStr Prostate Cancer Theranostics - An Overview
title_full_unstemmed Prostate Cancer Theranostics - An Overview
title_short Prostate Cancer Theranostics - An Overview
title_sort prostate cancer theranostics - an overview
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290246/
https://www.ncbi.nlm.nih.gov/pubmed/32582550
http://dx.doi.org/10.3389/fonc.2020.00884
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