Cargando…

HLA-DPB1 Reactive T Cell Receptors for Adoptive Immunotherapy in Allogeneic Stem Cell Transplantation

HLA-DPB1 antigens are mismatched in about 80% of allogeneic hematopoietic stem cell transplantations from HLA 10/10 matched unrelated donors and were shown to be associated with a decreased risk of leukemia relapse. We recently developed a reliable in vitro method to generate HLA-DPB1 mismatch-react...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klobuch, Sebastian, Hammon, Kathrin, Vatter-Leising, Sarah, Neidlinger, Elisabeth, Zwerger, Michael, Wandel, Annika, Neuber, Laura Maria, Heilmeier, Bernhard, Fichtner, Regina, Mirbeth, Carina, Herr, Wolfgang, Thomas, Simone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290340/ https://www.ncbi.nlm.nih.gov/pubmed/32443793 http://dx.doi.org/10.3390/cells9051264

Ejemplares similares

Biomodulatory Treatment With Azacitidine, All-trans Retinoic Acid and Pioglitazone Induces Differentiation of Primary AML Blasts Into Neutrophil Like Cells Capable of ROS Production and Phagocytosis
por: Klobuch, Sebastian, et al.
Publicado: (2018)

Influence of HLA-DPB1 mismatches on outcome after allogeneic hematopoietic stem cell transplantation
por: Hunziker, Mireille, et al.
Publicado: (2021)

Overexpressed Pseudogene HLA-DPB2 Promotes Tumor Immune Infiltrates by Regulating HLA-DPB1 and Indicates a Better Prognosis in Breast Cancer
por: Lyu, Lijuan, et al.
Publicado: (2020)

HLA-associated susceptibility to childhood B-cell precursor ALL: definition and role of HLA-DPB1 supertypes
por: Taylor, G M, et al.
Publicado: (2008)

HLA-DPB1*03 as Risk Allele and HLA-DPB1*04 as Protective Allele for Both Early- and Adult-Onset Multiple Sclerosis in a Hellenic Cohort
por: Anagnostouli, Maria, et al.
Publicado: (2020)

Classical HLA-DRB1 and DPB1 Alleles Account for HLA Associations with Primary Biliary Cirrhosis
por: Invernizzi, Pietro, et al.
Publicado: (2012)

A Polymorphism in the HLA-DPB1 Gene Is Associated with Susceptibility to Multiple Sclerosis
por: Field, Judith, et al.
Publicado: (2010)

Association of HLA-DPB1 with Scleroderma and Its Clinical Features in Chinese Population
por: Wang, Jiucun, et al.
Publicado: (2014)

Refined HLA-DPB1 mismatch with molecular algorithms predicts outcomes in hematopoietic stem cell transplantation
por: Zou, Jun, et al.
Publicado: (2021)

Assessment of HLA-DPB1 genetic variation using an HLA-DP tool and its implications in clinical transplantation
por: Sajulga, Ray, et al.
Publicado: (2023)

Risk-associations between HLA-DPB1 T cell epitope matching and outcome of unrelated hematopoietic cell transplantation are independent from HLA-DPA1
por: Fleischhauer, Katharina, et al.
Publicado: (2014)

The SNP rs3128965 of HLA-DPB1 as a Genetic Marker of the AERD Phenotype
por: Kim, Seung-Hyun, et al.
Publicado: (2014)

Independent association of HLA-DPB1*02:01 with rheumatoid arthritis in Japanese populations
por: Furukawa, Hiroshi, et al.
Publicado: (2018)

HLA-DPB1 alleles in hepatitis B vaccine response: A meta-analysis
por: Ou, Guojin, et al.
Publicado: (2021)

Characterization of the novel HLA‐DPB1*1348:01 allele by sequencing‐based typing
por: Cargou, Marine, et al.
Publicado: (2022)

Integrating biological HLA-DPB1 mismatch models to predict survival after unrelated hematopoietic cell transplantation
por: Ruggeri, Annalisa, et al.
Publicado: (2022)

HLA Class II Genes HLA-DRB1, HLA-DPB1, and HLA-DQB1 Are Associated With the Antibody Response to Inactivated Japanese Encephalitis Vaccine
por: Yao, Yufeng, et al.
Publicado: (2019)

Characterization of the novel HLA‐DPB1*11:01:06 allele by sequencing‐based typing
por: Cargou, Marine, et al.
Publicado: (2022)

HLA-mismatched allogeneic adoptive immune therapy in severely immunosuppressed AIDS patients
por: Xu, Ruonan, et al.
Publicado: (2021)

Dissecting Genetic Control of HLA-DPB1 Expression and Its Relation to Structural Mismatch Models in Hematopoietic Stem Cell Transplantation
por: Meurer, Thuja, et al.
Publicado: (2018)

Protective Effect of HLA-DPB1 Mismatch Remains Valid in Reduced-Intensity Conditioning Unrelated Donor Hematopoietic Cell Transplantation
por: Malki, Monzr M. Al, et al.
Publicado: (2019)

A cis-eQTL of HLA-DPB1 Affects Susceptibility to Type 1 Autoimmune Hepatitis
por: Yamazaki, Tomoo, et al.
Publicado: (2018)

Performance of HLA allele prediction methods in African Americans for class II genes HLA-DRB1, −DQB1, and –DPB1
por: Levin, Albert M, et al.
Publicado: (2014)

HLA alleles, especially amino-acid signatures of HLA-DPB1, might contribute to the molecular pathogenesis of early-onset autoimmune thyroid disease
por: Shin, Dong-Hwan, et al.
Publicado: (2019)

HLA-DPB1 and Epstein-Barr virus gp42 protein jointly contribute to the development of Hodgkin lymphoma
por: Li, Hongyu, et al.
Publicado: (2020)

HLA-DPB1 rs9277535 polymorphism is associated with rheumatoid arthritis risk in a Chinese Han population
por: Yang, Zhicheng, et al.
Publicado: (2021)

Allorecognition of HLA-C Mismatches by CD8(+) T Cells in Hematopoietic Stem Cell Transplantation Is a Complex Interplay between Mismatched Peptide-Binding Region Residues, HLA-C Expression, and HLA-DPB1 Disparities
por: Bettens, Florence, et al.
Publicado: (2016)

Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice
por: Thomas, Simone, et al.
Publicado: (2015)

Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver
por: O'Brien, T R, et al.
Publicado: (2011)

Transancestral mapping of the MHC region in systemic lupus erythematosus identifies new independent and interacting loci at MSH5, HLA-DPB1 and HLA-G
por: Fernando, Michelle M A, et al.
Publicado: (2012)

A Phase I study of an HLA-DPB1*0401-restricted T cell receptor targeting MAGE-A3 for patients with metastatic cancers
por: Lu, Yong-Chen, et al.
Publicado: (2015)

A combined DPA1∼DPB1 amino acid epitope is the primary unit of selection on the HLA-DP heterodimer
por: Hollenbach, Jill A., et al.
Publicado: (2012)

Association of HLA-DPA1, HLA-DPB1, and HLA-DQB1 Alleles With the Long-Term and Booster Immune Responses of Young Adults Vaccinated Against the Hepatitis B Virus as Neonates
por: Wang, Wen-Chang, et al.
Publicado: (2021)

Further investigation of the role of HLA-DPB1 in adult Hodgkin's disease (HD) suggests an influence on susceptibility to different HD subtypes
por: Taylor, G M, et al.
Publicado: (1999)

HLA-DPB1 Variant Effect on Hepatitis B Virus Clearance and Liver Cirrhosis Development Among Southwest Chinese Population
por: Hu, Zhangyong, et al.
Publicado: (2014)

The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability
por: Isoz, Isabelle, et al.
Publicado: (2012)

The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients
por: Luo, Huan, et al.
Publicado: (2011)

Integrated transcriptomic and regulatory network analyses uncovers the role of let-7b-5p, SPIB, and HLA-DPB1 in sepsis
por: Mohsin, Mohd, et al.
Publicado: (2022)

IL6-receptor antibody tocilizumab as salvage therapy in severe chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: a retrospective analysis
por: Kattner, Anna-Sophia, et al.
Publicado: (2020)

METTL16 regulates m(6)A methylation on chronic hepatitis B associated gene HLA-DPB1 involved in liver fibrosis
por: Gao, Haibing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bngb88hbbmem3r1cctg33h9gfj