Human Induced Pluripotent Stem Cell-Derived 3D-Neurospheres Are Suitable for Neurotoxicity Screening

We present a hiPSC-based 3D in vitro system suitable to test neurotoxicity (NT). Human iPSCs-derived 3D neurospheres grown in 96-well plate format were characterized timewise for 6-weeks. Changes in complexity and homogeneity were followed by immunocytochemistry and transmission electron microscopy....

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Detalles Bibliográficos
Autores principales: Kobolak, Julianna, Teglasi, Annamaria, Bellak, Tamas, Janstova, Zofia, Molnar, Kinga, Zana, Melinda, Bock, Istvan, Laszlo, Lajos, Dinnyes, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290365/
https://www.ncbi.nlm.nih.gov/pubmed/32369990
http://dx.doi.org/10.3390/cells9051122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290365/
https://www.ncbi.nlm.nih.gov/pubmed/32369990
http://dx.doi.org/10.3390/cells9051122

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