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HDAC3–ERα Selectively Regulates TNF-α-Induced Apoptotic Cell Death in MCF-7 Human Breast Cancer Cells via the p53 Signaling Pathway

Tumor necrosis factor-α (TNF-α) plays a significant role in inflammation and cancer-related apoptosis. We identified a TNF-α-mediated epigenetic mechanism of apoptotic cell death regulation in estrogen receptor-α (ERα)-positive human breast cancer cells. To assess the apoptotic effect of TNF-α, anne...

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Detalles Bibliográficos
Autores principales:	Park, Seung-Ho, Kim, Hyunhee, Kwak, Sungmin, Jeong, Ji-Hoon, Lee, Jangho, Hwang, Jin-Taek, Choi, Hyo-Kyoung, Choi, Kyung-Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290399/ https://www.ncbi.nlm.nih.gov/pubmed/32455774 http://dx.doi.org/10.3390/cells9051280

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