Cargando…
Genome Editing of the SNAI1 Gene in Rhabdomyosarcoma: A Novel Model for Studies of Its Role
Genome editing (GE) tools and RNA interference technology enable the modulation of gene expression in cancer research. While GE mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 or transcription activator-like effector nucleases (TALEN) activity can be used to induc...
Autores principales: | Ulman, Aleksandra, Skrzypek, Klaudia, Konieczny, Paweł, Mussolino, Claudio, Cathomen, Toni, Majka, Marcin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290443/ https://www.ncbi.nlm.nih.gov/pubmed/32354171 http://dx.doi.org/10.3390/cells9051095 |
Ejemplares similares
-
SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function
por: Skrzypek, Klaudia, et al.
Publicado: (2018) -
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
por: Mussolino, Claudio, et al.
Publicado: (2011) -
SNAIL Promotes Metastatic Behavior of Rhabdomyosarcoma by Increasing EZRIN and AKT Expression and Regulating MicroRNA Networks
por: Skrzypek, Klaudia, et al.
Publicado: (2020) -
Traceless Targeting and Isolation of Gene-Edited Immortalized Keratinocytes from Epidermolysis Bullosa Simplex Patients
por: Aushev, Magomet, et al.
Publicado: (2017) -
Constitutive activation of MET signaling impairs myogenic differentiation of rhabdomyosarcoma and promotes its development and progression
por: Skrzypek, Klaudia, et al.
Publicado: (2015)