Repurposing Cancer Drugs Batimastat and Marimastat to Inhibit the Activity of a Group I Metalloprotease from the Venom of the Western Diamondback Rattlesnake, Crotalus atrox

Snakebite envenomation causes over 140,000 deaths every year, predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases. It is associated with incredibly complex pathophysiology due to the vast number of unique toxins/proteins present in the venoms...

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Detalles Bibliográficos
Autores principales: Layfield, Harry J., Williams, Harry F., Ravishankar, Divyashree, Mehmi, Amita, Sonavane, Medha, Salim, Anika, Vaiyapuri, Rajendran, Lakshminarayanan, Karthik, Vallance, Thomas M., Bicknell, Andrew B., Trim, Steven A., Patel, Ketan, Vaiyapuri, Sakthivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290494/
https://www.ncbi.nlm.nih.gov/pubmed/32397419
http://dx.doi.org/10.3390/toxins12050309

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