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Cnf1 Variants Endowed with the Ability to Cross the Blood–Brain Barrier: A New Potential Therapeutic Strategy for Glioblastoma
Among gliomas, primary tumors originating from glial cells, glioblastoma (GBM) identified as WHO grade IV glioma, is the most common and aggressive malignant brain tumor. We have previously shown that the Escherichia coli protein toxin cytotoxic necrotizing factor 1 (CNF1) is remarkably effective as...
Autores principales: | Colarusso, Andrea, Maroccia, Zaira, Parrilli, Ermenegilda, Germinario, Elena Angela Pia, Fortuna, Andrea, Loizzo, Stefano, Ricceri, Laura, Tutino, Maria Luisa, Fiorentini, Carla, Fabbri, Alessia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290510/ https://www.ncbi.nlm.nih.gov/pubmed/32375387 http://dx.doi.org/10.3390/toxins12050291 |
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