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A deep learning, image based approach for automated diagnosis for inflammatory skin diseases

BACKGROUND: As the booming of deep learning era, especially the advances in convolutional neural networks (CNNs), CNNs have been applied in medicine fields like radiology and pathology. However, the application of CNNs in dermatology, which is also based on images, is very limited. Inflammatory skin...

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Autores principales: Wu, Haijing, Yin, Heng, Chen, Haipeng, Sun, Moyuan, Liu, Xiaoqing, Yu, Yizhou, Tang, Yang, Long, Hai, Zhang, Bo, Zhang, Jing, Zhou, Ying, Li, Yaping, Zhang, Guiyuing, Zhang, Peng, Zhan, Yi, Liao, Jieyue, Luo, Shuaihantian, Xiao, Rong, Su, Yuwen, Zhao, Juanjuan, Wang, Fei, Zhang, Wei, Zhang, Jin, Lu, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290553/
https://www.ncbi.nlm.nih.gov/pubmed/32566608
http://dx.doi.org/10.21037/atm.2020.04.39
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author Wu, Haijing
Yin, Heng
Chen, Haipeng
Sun, Moyuan
Liu, Xiaoqing
Yu, Yizhou
Tang, Yang
Long, Hai
Zhang, Bo
Zhang, Jing
Zhou, Ying
Li, Yaping
Zhang, Guiyuing
Zhang, Peng
Zhan, Yi
Liao, Jieyue
Luo, Shuaihantian
Xiao, Rong
Su, Yuwen
Zhao, Juanjuan
Wang, Fei
Zhang, Jing
Zhang, Wei
Zhang, Jin
Lu, Qianjin
author_facet Wu, Haijing
Yin, Heng
Chen, Haipeng
Sun, Moyuan
Liu, Xiaoqing
Yu, Yizhou
Tang, Yang
Long, Hai
Zhang, Bo
Zhang, Jing
Zhou, Ying
Li, Yaping
Zhang, Guiyuing
Zhang, Peng
Zhan, Yi
Liao, Jieyue
Luo, Shuaihantian
Xiao, Rong
Su, Yuwen
Zhao, Juanjuan
Wang, Fei
Zhang, Jing
Zhang, Wei
Zhang, Jin
Lu, Qianjin
author_sort Wu, Haijing
collection PubMed
description BACKGROUND: As the booming of deep learning era, especially the advances in convolutional neural networks (CNNs), CNNs have been applied in medicine fields like radiology and pathology. However, the application of CNNs in dermatology, which is also based on images, is very limited. Inflammatory skin diseases, such as psoriasis (Pso), eczema (Ecz), and atopic dermatitis (AD), are very easily to be mis-diagnosed in practice. METHODS: Based on the EfficientNet-b4 CNN algorithm, we developed an artificial intelligence dermatology diagnosis assistant (AIDDA) for Pso, Ecz & AD and healthy skins (HC). The proposed CNN model was trained based on 4,740 clinical images, and the performance was evaluated on experts-confirmed clinical images grouped into 3 different dermatologist-labelled diagnosis classifications (HC, Pso, Ecz & AD). RESULTS: The overall diagnosis accuracy of AIDDA is 95.80%±0.09%, with the sensitivity of 94.40%±0.12% and specificity 97.20%±0.06%. AIDDA showed accuracy for Pso is 89.46%, with sensitivity of 91.4% and specificity of 95.48%, and accuracy for AD & Ecz 92.57%, with sensitivity of 94.56% and specificity of 94.41%. CONCLUSIONS: AIDDA is thus already achieving an impact in the diagnosis of inflammatory skin diseases, highlighting how deep learning network tools can help advance clinical practice.
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spelling pubmed-72905532020-06-19 A deep learning, image based approach for automated diagnosis for inflammatory skin diseases Wu, Haijing Yin, Heng Chen, Haipeng Sun, Moyuan Liu, Xiaoqing Yu, Yizhou Tang, Yang Long, Hai Zhang, Bo Zhang, Jing Zhou, Ying Li, Yaping Zhang, Guiyuing Zhang, Peng Zhan, Yi Liao, Jieyue Luo, Shuaihantian Xiao, Rong Su, Yuwen Zhao, Juanjuan Wang, Fei Zhang, Jing Zhang, Wei Zhang, Jin Lu, Qianjin Ann Transl Med Original Article BACKGROUND: As the booming of deep learning era, especially the advances in convolutional neural networks (CNNs), CNNs have been applied in medicine fields like radiology and pathology. However, the application of CNNs in dermatology, which is also based on images, is very limited. Inflammatory skin diseases, such as psoriasis (Pso), eczema (Ecz), and atopic dermatitis (AD), are very easily to be mis-diagnosed in practice. METHODS: Based on the EfficientNet-b4 CNN algorithm, we developed an artificial intelligence dermatology diagnosis assistant (AIDDA) for Pso, Ecz & AD and healthy skins (HC). The proposed CNN model was trained based on 4,740 clinical images, and the performance was evaluated on experts-confirmed clinical images grouped into 3 different dermatologist-labelled diagnosis classifications (HC, Pso, Ecz & AD). RESULTS: The overall diagnosis accuracy of AIDDA is 95.80%±0.09%, with the sensitivity of 94.40%±0.12% and specificity 97.20%±0.06%. AIDDA showed accuracy for Pso is 89.46%, with sensitivity of 91.4% and specificity of 95.48%, and accuracy for AD & Ecz 92.57%, with sensitivity of 94.56% and specificity of 94.41%. CONCLUSIONS: AIDDA is thus already achieving an impact in the diagnosis of inflammatory skin diseases, highlighting how deep learning network tools can help advance clinical practice. AME Publishing Company 2020-05 /pmc/articles/PMC7290553/ /pubmed/32566608 http://dx.doi.org/10.21037/atm.2020.04.39 Text en 2020 Annals of Translational Medicine. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Wu, Haijing
Yin, Heng
Chen, Haipeng
Sun, Moyuan
Liu, Xiaoqing
Yu, Yizhou
Tang, Yang
Long, Hai
Zhang, Bo
Zhang, Jing
Zhou, Ying
Li, Yaping
Zhang, Guiyuing
Zhang, Peng
Zhan, Yi
Liao, Jieyue
Luo, Shuaihantian
Xiao, Rong
Su, Yuwen
Zhao, Juanjuan
Wang, Fei
Zhang, Jing
Zhang, Wei
Zhang, Jin
Lu, Qianjin
A deep learning, image based approach for automated diagnosis for inflammatory skin diseases
title A deep learning, image based approach for automated diagnosis for inflammatory skin diseases
title_full A deep learning, image based approach for automated diagnosis for inflammatory skin diseases
title_fullStr A deep learning, image based approach for automated diagnosis for inflammatory skin diseases
title_full_unstemmed A deep learning, image based approach for automated diagnosis for inflammatory skin diseases
title_short A deep learning, image based approach for automated diagnosis for inflammatory skin diseases
title_sort deep learning, image based approach for automated diagnosis for inflammatory skin diseases
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290553/
https://www.ncbi.nlm.nih.gov/pubmed/32566608
http://dx.doi.org/10.21037/atm.2020.04.39
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