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The Detrimental Action of Adenosine on Glutamate-Induced Cytotoxicity in PC12 Cells Can Be Shifted towards a Neuroprotective Role through A(1)AR Positive Allosteric Modulation

Glutamate cytotoxicity is implicated in neuronal death in different neurological disorders including stroke, traumatic brain injury, and neurodegenerative diseases. Adenosine is a nucleoside that plays an important role in modulating neuronal activity and its receptors have been identified as promis...

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Detalles Bibliográficos
Autores principales: Vincenzi, Fabrizio, Pasquini, Silvia, Gessi, Stefania, Merighi, Stefania, Romagnoli, Romeo, Borea, Pier Andrea, Varani, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290574/
https://www.ncbi.nlm.nih.gov/pubmed/32443448
http://dx.doi.org/10.3390/cells9051242