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Sorting Nexin 27 Regulates the Lysosomal Degradation of Aquaporin-2 Protein in the Kidney Collecting Duct

Sorting nexin 27 (SNX27), a PDZ (Postsynaptic density-95/Discs large/Zonula occludens 1) domain-containing protein, cooperates with a retromer complex, which regulates intracellular trafficking and the abundance of membrane proteins. Since the carboxyl terminus of aquaporin-2 (AQP2c) has a class I P...

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Detalles Bibliográficos
Autores principales:	Choi, Hyo-Jung, Jang, Hyo-Ju, Park, Euijung, Tingskov, Stine Julie, Nørregaard, Rikke, Jung, Hyun Jun, Kwon, Tae-Hwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290579/ https://www.ncbi.nlm.nih.gov/pubmed/32413996 http://dx.doi.org/10.3390/cells9051208

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