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Significant Differences in RNA Structure Destabilization by HIV-1 Gag∆p6 and NCp7 Proteins
Retroviral nucleocapsid (NC) proteins are nucleic acid chaperones that play distinct roles in the viral life cycle. During reverse transcription, HIV-1 NC facilitates the rearrangement of nucleic acid secondary structures, allowing the transactivation response (TAR) RNA hairpin to be transiently des...
Autores principales: | McCauley, Micah J., Rouzina, Ioulia, Li, Jasmine, Núñez, Megan E., Williams, Mark C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290599/ https://www.ncbi.nlm.nih.gov/pubmed/32344834 http://dx.doi.org/10.3390/v12050484 |
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