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Alzheimer’s Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor α

Alzheimer’s disease (AD) is the leading cause of dementia in the elderly. Mutations in genes encoding proteins involved in amyloid-β peptide (Aβ) production are responsible for inherited AD cases. The amyloid cascade hypothesis was proposed to explain the pathogeny. Despite the fact that Aβ is consi...

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Detalles Bibliográficos
Autores principales: Sáez-Orellana, Francisco, Octave, Jean-Noël, Pierrot, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290654/
https://www.ncbi.nlm.nih.gov/pubmed/32422896
http://dx.doi.org/10.3390/cells9051215