Impairment of Proteasome and Autophagy Underlying the Pathogenesis of Leukodystrophy

Impairment of the ubiquitin-proteasome-system (UPS) and autophagy causing cytoplasmic aggregation of ubiquitin andp62 have been implicated in the pathogenesis of most neurodegenerative disorders, yet, they have not been fully elucidated in leukodystrophies. The relationship among impairment of UPS,...

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Detalles Bibliográficos
Autores principales: Lin, Dar-Shong, Ho, Che-Sheng, Huang, Yu-Wen, Wu, Tsu-Yen, Lee, Tsung-Han, Huang, Zo-Darr, Wang, Tuan-Jen, Yang, Shun-Jie, Chiang, Ming-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290671/
https://www.ncbi.nlm.nih.gov/pubmed/32370022
http://dx.doi.org/10.3390/cells9051124

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