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An Elvitegravir Nanoformulation Crosses the Blood–Brain Barrier and Suppresses HIV-1 Replication in Microglia

Even with an efficient combination of antiretroviral therapy (ART), which significantly decreases viral load in human immunodeficiency virus type 1 (HIV-1)-positive individuals, the occurrence of HIV-1-associated neurocognitive disorders (HAND) still exists. Microglia have been shown to have a signi...

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Detalles Bibliográficos
Autores principales: Gong, Yuqing, Zhi, Kaining, Nagesh, Prashanth K. B., Sinha, Namita, Chowdhury, Pallabita, Chen, Hao, Gorantla, Santhi, Yallapu, Murali M., Kumar, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290679/
https://www.ncbi.nlm.nih.gov/pubmed/32443728
http://dx.doi.org/10.3390/v12050564