Cargando…

Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States

Background: This study aimed to assess the risk factors and impact of acute myocardial infarction on in-hospital treatments, complications, outcomes, and resource utilization in hospitalized patients for heat stroke in the United States. Methods: Hospitalized patients with a principal diagnosis of h...

Descripción completa

Detalles Bibliográficos
Autores principales: Bathini, Tarun, Thongprayoon, Charat, Chewcharat, Api, Petnak, Tananchai, Cheungpasitporn, Wisit, Boonpheng, Boonphiphop, Prasitlumkum, Narut, Chokesuwattanaskul, Ronpichai, Vallabhajosyula, Saraschandra, Kaewput, Wisit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290741/
https://www.ncbi.nlm.nih.gov/pubmed/32384601
http://dx.doi.org/10.3390/jcm9051357
_version_ 1783545747134742528
author Bathini, Tarun
Thongprayoon, Charat
Chewcharat, Api
Petnak, Tananchai
Cheungpasitporn, Wisit
Boonpheng, Boonphiphop
Prasitlumkum, Narut
Chokesuwattanaskul, Ronpichai
Vallabhajosyula, Saraschandra
Kaewput, Wisit
author_facet Bathini, Tarun
Thongprayoon, Charat
Chewcharat, Api
Petnak, Tananchai
Cheungpasitporn, Wisit
Boonpheng, Boonphiphop
Prasitlumkum, Narut
Chokesuwattanaskul, Ronpichai
Vallabhajosyula, Saraschandra
Kaewput, Wisit
author_sort Bathini, Tarun
collection PubMed
description Background: This study aimed to assess the risk factors and impact of acute myocardial infarction on in-hospital treatments, complications, outcomes, and resource utilization in hospitalized patients for heat stroke in the United States. Methods: Hospitalized patients with a principal diagnosis of heat stroke were identified in the National Inpatient Sample dataset from the years 2003 to 2014. Acute myocardial infarction was identified using the hospital International Classification of Diseases, Ninth Revision (ICD-9), diagnosis of 410.xx. Clinical characteristics, in-hospital treatment, complications, outcomes, and resource utilization between patients with and without acute myocardial infarction were compared. Results: A total of 3372 heat stroke patients were included in the analysis. Of these, acute myocardial infarction occurred in 225 (7%) admissions. Acute myocardial infarction occurred more commonly in obese female patients with a history of chronic kidney disease, but less often in male patients aged <20 years with a history of hypothyroidism. The need for mechanical ventilation, blood transfusion, and renal replacement therapy were higher in patients with acute myocardial infarction. Acute myocardial infarction was associated with rhabdomyolysis, metabolic acidosis, sepsis, gastrointestinal bleeding, ventricular arrhythmia or cardiac arrest, renal failure, respiratory failure, circulatory failure, liver failure, neurological failure, and hematologic failure. Patients with acute myocardial infarction had 5.2-times greater odds of in-hospital mortality than those without myocardial infarction. The length of hospital stay and hospitalization cost were also higher when an acute myocardial infarction occurred while hospitalized. Conclusion: Acute myocardial infarction was associated with worse outcomes and higher economic burden among patients hospitalized for heat stroke. Obesity and chronic kidney disease were associated with increased risk of acute myocardial infarction, while young male patients and hypothyroidism were associated with decreased risk.
format Online
Article
Text
id pubmed-7290741
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-72907412020-06-17 Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States Bathini, Tarun Thongprayoon, Charat Chewcharat, Api Petnak, Tananchai Cheungpasitporn, Wisit Boonpheng, Boonphiphop Prasitlumkum, Narut Chokesuwattanaskul, Ronpichai Vallabhajosyula, Saraschandra Kaewput, Wisit J Clin Med Article Background: This study aimed to assess the risk factors and impact of acute myocardial infarction on in-hospital treatments, complications, outcomes, and resource utilization in hospitalized patients for heat stroke in the United States. Methods: Hospitalized patients with a principal diagnosis of heat stroke were identified in the National Inpatient Sample dataset from the years 2003 to 2014. Acute myocardial infarction was identified using the hospital International Classification of Diseases, Ninth Revision (ICD-9), diagnosis of 410.xx. Clinical characteristics, in-hospital treatment, complications, outcomes, and resource utilization between patients with and without acute myocardial infarction were compared. Results: A total of 3372 heat stroke patients were included in the analysis. Of these, acute myocardial infarction occurred in 225 (7%) admissions. Acute myocardial infarction occurred more commonly in obese female patients with a history of chronic kidney disease, but less often in male patients aged <20 years with a history of hypothyroidism. The need for mechanical ventilation, blood transfusion, and renal replacement therapy were higher in patients with acute myocardial infarction. Acute myocardial infarction was associated with rhabdomyolysis, metabolic acidosis, sepsis, gastrointestinal bleeding, ventricular arrhythmia or cardiac arrest, renal failure, respiratory failure, circulatory failure, liver failure, neurological failure, and hematologic failure. Patients with acute myocardial infarction had 5.2-times greater odds of in-hospital mortality than those without myocardial infarction. The length of hospital stay and hospitalization cost were also higher when an acute myocardial infarction occurred while hospitalized. Conclusion: Acute myocardial infarction was associated with worse outcomes and higher economic burden among patients hospitalized for heat stroke. Obesity and chronic kidney disease were associated with increased risk of acute myocardial infarction, while young male patients and hypothyroidism were associated with decreased risk. MDPI 2020-05-06 /pmc/articles/PMC7290741/ /pubmed/32384601 http://dx.doi.org/10.3390/jcm9051357 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bathini, Tarun
Thongprayoon, Charat
Chewcharat, Api
Petnak, Tananchai
Cheungpasitporn, Wisit
Boonpheng, Boonphiphop
Prasitlumkum, Narut
Chokesuwattanaskul, Ronpichai
Vallabhajosyula, Saraschandra
Kaewput, Wisit
Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States
title Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States
title_full Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States
title_fullStr Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States
title_full_unstemmed Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States
title_short Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States
title_sort acute myocardial infarction among hospitalizations for heat stroke in the united states
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290741/
https://www.ncbi.nlm.nih.gov/pubmed/32384601
http://dx.doi.org/10.3390/jcm9051357
work_keys_str_mv AT bathinitarun acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates
AT thongprayooncharat acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates
AT chewcharatapi acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates
AT petnaktananchai acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates
AT cheungpasitpornwisit acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates
AT boonphengboonphiphop acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates
AT prasitlumkumnarut acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates
AT chokesuwattanaskulronpichai acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates
AT vallabhajosyulasaraschandra acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates
AT kaewputwisit acutemyocardialinfarctionamonghospitalizationsforheatstrokeintheunitedstates